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Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer


Cancer-related fatigue (CRF) is a common and relevant symptom in patients with advanced cancer that significantly decreases their quality of life. The aim of this study was to evaluate the effect of a physiotherapy programme on CRF and other symptoms in patients diagnosed with advanced cancer.

Concepts: Cancer, Oncology, Medical terms, Randomized controlled trial, Symptom, Symptomatic treatment, Fatigue, Post-concussion syndrome


Patients with brain tumors constitute a vulnerable group, and it is important that they receive the highest quality of care (QoC). The study aim was to describe the perceptions of QoC and its association with health-related quality of life in brain tumor patients undergoing proton beam therapy in a newly established clinic.


This study evaluated the attitudes of cancer patients' family members regarding disclosure of a cancer diagnosis to the patient and justifications for their attitudes.

Concepts: Medical terms, Patient, Hospital, Truth, Physician, Patience, De facto


Neurotoxicity is a common side-effect of cancer treatment, but no scales have been validated for the pediatric population. The objective of this study was to test the reliability and validity of the pediatric modified-Total Neuropathy Scale (ped-mTNS) to measure chemotherapy-induced peripheral neuropathy in school-aged children.

Concepts: Chemotherapy, Psychometrics, Reliability


Cancer and its treatments are associated with psychological distress that can negatively impact self-perception, psychosocial functioning, and quality of life. Patients with head and neck cancers (HNC) are particularly susceptible to psychological distress. This study involved a cross-validation of the Measure of Body Apperception (MBA) for HNC patients.

Concepts: Scientific method, Head and neck anatomy, Head and neck, Cancer, Oncology, Life, Head and neck cancer, Cancer research


Cancer cachexia and low energy intake (EI) probably contribute to weight loss in advanced pancreatic cancer (PC). However, little is known about the actual EI in this disease. Aims were to assess EI, weight loss and symptoms during the disease course and investigate associations between symptoms and EI.

Concepts: Cancer, Disease, Obesity, Symptoms, Symptom, Cachexia, Weight loss, Pancreatic cancer


PURPOSE: The aim of this study was to provide the first prospective longitudinal assessment of anxiety and depression in patients with a benign intracranial meningioma (WHO° I). METHODS: The Hospital Anxiety and Depression Scale was applied prior to (t1) and directly after (t2) neurosurgery as well as 6 months after surgery (t3). The research was conducted in a single treatment centre in Germany. Numerous sociodemographic, medical, psychological and cognitive accompanying measures were assessed. The study population consisted of 52 meningioma patients. Additionally, a control group of 24 patients with malignant brain tumours (astrocytoma WHO° III) was assessed. RESULTS: In meningioma patients, anxiety was high prior to surgery but declined significantly after successful neurosurgical treatment. Low levels of depression were observed at all times. In contrast, astrocytoma patients showed constantly high levels of anxiety whilst depression increased over the course of the disease. Numerous medical, psychosocial and psychological factors were associated with psychiatric morbidity in meningioma patients. CONCLUSIONS: In conclusion, psychiatric morbidity of patients with benign intracranial meningiomas was comparable to that of the general population after successful neurosurgical treatment. Numerous associated factors suggest complex relationships within a biopsychosocial model. However, due to the small sample size and recruitment in a single institution, our results are of limited generalisability and need cross-validation in future studies.

Concepts: Psychology, Sample size, Surgery, Brain tumor, Neurosurgery, Psychiatry, Meningioma, Biopsychosocial model


Cachexia in patients with hematological malignancies is often related to sarcopenia. We believe that allogeneic hematopoietic stem cell transplant (allo-HSCT) patients often exhibit sarcopenia prior to transplantation. Here, we aimed to investigate the prevalence of sarcopenia and its relationship with body composition, physiological function, nutrition, fatigue, and health-related quality of life (QOL) in patients before allo-HSCT. We further investigated the confounding factors associated with sarcopenia.

Concepts: Cancer, Bone marrow, Chemotherapy, Hematology, Organ transplant, Hematopoietic stem cell transplantation, Hematopoietic stem cell, Hematological malignancy


The purpose of this project was to evaluate research in basic oral care interventions to update evidence-based practice guidelines for preventing and treating oral mucositis (OM) in cancer patients undergoing radio- or chemotherapy.

Concepts: Oncology, Chemotherapy, Hematopoietic stem cell transplantation, Mucositis


The Impact of Cancer Scale (IOC) is a self-assessment tool designed to capture the unique and multidimensional aspects of the quality of life of long-term cancer survivors. This paper describes the adaptation and psychometric evaluation of its Italian version.

Concepts: Cancer, Life, Evaluation