SciCombinator

Discover the most talked about and latest scientific content & concepts.

Journal: Revista espanola de anestesiologia y reanimacion

27

To perform a meta-analysis on the use of combined epidural-intrathecal analgesia during labor, including intrathecal fentanyl and/or morphine compared to usual epidural techniques.

Concepts: Systematic review, Morphine, Heroin, Meta-analysis, Epidural, Pethidine, Analgesics

25

Intraoperative evaluation of analgesia remains today often based on heart rate and arterial pressure fluctuations. None of these parameters is specific. Incorrect handling during this process may increase surgical morbi-mortality of the patients and their acute postoperative pain. The aim of this study was to evaluate the impact of intraoperative analgesia controlled by pupillometry on postoperative analgesic consumption and the pain intensity in the first 12h in the hospital room, after major gynecological surgery.

Concepts: Hospital, Physician, Opioid, Pain, Analgesic

25

There is an almost unanimous consensus on the management of the direct new oral anticoagulants, dabigatran, rivaroxaban, and apixaban in elective surgery. However, this general consensus does not exist in relation with the direct new oral anticoagulants use in emergency surgery, especially in the bleeding patient. For this reason, a literature review was performed using the MEDLINE-PubMed. An analysis was made of the journal articles, reviews, systematic reviews, and practices guidelines published between 2000 and 2014 using the terms “monitoring” and “reversal”. From this review, it was shown that the routine tests of blood coagulation, such as the prothrombin time and activated partial thromboplastin time, have a limited efficacy in the perioperative control of blood coagulation in these patients. There is currently no antidote to reverse the effects of these drugs, although the possibility of using concentrated prothrombin complex and recombinant activated factor vii has been suggested for the urgent reversal of the anticoagulant effect.

Concepts: Coagulation, Warfarin, Anticoagulant, Heparin, Blood transfusion, Prothrombin time, Vitamin K, Direct thrombin inhibitor

25

25

To analyse the trend in lipid peroxidation and antioxidant response as key markers of oxidative stress after paediatric cardiovascular surgery, and compare them with other internationally accepted clinical prognostic indicators.

Concepts: Medicine, Antioxidant, Oxidative stress, Oxidative phosphorylation, Reactive oxygen species, Cardiothoracic surgery, Lipid peroxidation, Vitamin E

25

Tranexamic acid (TXA) is an antifibrinolytic drug used to reduce bleeding in mortality risk situations such as trauma, cardiovascular surgery, and orthopedic surgery. The objective is to evaluate the effectiveness and safety of TXA in reducing surgery bleeding in hip arthroplasty through a systematic review of literature.

Concepts: Carbon dioxide, Blood, Hip replacement, Orthopedic surgery, Joint replacement, Tranexamic acid, Antifibrinolytic, John Charnley

24

The aim of the study was to assess the effectiveness of ultrasound-guided transversalis fascia plane block (TFP) compared to anterior transversus abdominis plane block (TAP-A) for post-operative analgesia in outpatient unilateral inguinal hernia repair.

Concepts: Inguinal hernia, Transversus abdominis muscle, Iliac crest, Transversalis fascia

24

A case is presented on a patient who underwent left single lung transplantation for emphysema type COPD. There was early graft dysfunction gradeiii during the immediate postoperative period, which required the implantation of an extracorporeal membrane oxygenator (ECMO). Respirator ventilatory parameters were adjusted to avoid lung distension, low tidal volume (Vc) (280ml), high respiratory rates (20rpm), and a positive pressure at end expiration (PEEP) level of 8cmH2O. On monitoring the pulmonary tidal volume distribution by bedside electrical impedance tomography (EIT), it was noted that most of the tidal volume was distributed in the native lung emphysema. An alveolar recruitment manoeuvre was performed, under control of the EIT, that enabled the current volume and distribution and the pressures required to ventilate the transplanted lung to be observed.

Concepts: Pulmonology, Lung, Chronic obstructive pulmonary disease, Emphysema, Alpha 1-antitrypsin deficiency, Organ transplant, Pressure, Lung transplantation

22

To determine the relationship between the use of whole-body computed tomography (WB-CT) and hospital mortality in elderly patients with thoracic-abdominal-pelvic injury requiring admission to an intensive care unit.

Concepts: Hospital, Intensive care medicine, Geriatrics

1

To identify family doctor prescription patterns for strong opioids for chronic, non-cancer-related pain.