SciCombinator

Discover the most talked about and latest scientific content & concepts.

Journal: Neurology

420

To assess the association between Mediterranean-type diet (MeDi) and change in brain MRI volumetric measures and mean cortical thickness across a 3-year period in older age (73-76 years).

Concepts: Magnetic resonance imaging, Cerebral cortex, The Association, Sunshine pop

262

To investigate whether greater cardiovascular fitness in midlife is associated with decreased dementia risk in women followed up for 44 years.

Concepts: Sociology

198

To characterize effects of alemtuzumab treatment on measures of disability improvement in patients with relapsing-remitting multiple sclerosis (RRMS) with inadequate response (≥1 relapse) to prior therapy.

Concepts: Better, Improve, Multiple sclerosis

137

To examine whether vagotomy decreases the risk of Parkinson disease (PD).

Concepts: Parkinson's disease, James Parkinson

116

To increase understanding of the biological mechanisms underlying the association, we investigated the individual relations to cognitive decline of the primary nutrients and bioactives in green leafy vegetables, including vitamin K (phylloquinone), lutein, β-carotene, nitrate, folate, kaempferol, and α-tocopherol.

Concepts: Nutrition, Vitamin, Cognition, Vegetable, Leaf, Lettuce, Leaf vegetable, Spinach

102

To investigate the kinetics and metabolism of caffeine in serum from patients with Parkinson disease (PD) and controls using liquid chromatography-mass spectrometry.

Concepts: Metabolism, Mass spectrometry, Parkinson's disease, Tremor, James Parkinson

92

To evaluate the onset of efficacy of TEV-48125, a monoclonal antibody against calcitonin gene-related peptide, recently shown to be effective for the preventive treatment of chronic migraine (CM) and high-frequency episodic migraine.

Concepts: Calcitonin gene-related peptide

87

Stroke and TIA are recognized complications of acute herpes zoster (HZ). In this study, we evaluated HZ as a risk factor for cerebrovascular disease (stroke and TIA) and myocardial infarction (MI) in a UK population cohort.

Concepts: Cohort study, Epidemiology, Myocardial infarction, Atherosclerosis, Herpes zoster

80

To determine if blood neurofilament light chain (NfL) protein can discriminate between Parkinson disease (PD) and atypical parkinsonian disorders (APD) with equally high diagnostic accuracy as CSF NfL, and can therefore improve the diagnostic workup of parkinsonian disorders.

Concepts: Medical terms, Parkinson's disease, Parkinsonism, Multiple system atrophy

71

To predict the risk of probable dementia with Lewy bodies (DLB) competing with Alzheimer disease (AD) dementia by hippocampal volume (HV) in patients with mild cognitive impairment (MCI) with impairments in amnestic or nonamnestic cognitive domains.

Concepts: Alzheimer's disease, Memory, Parkinson's disease, Hippocampus, Dementia, Lewy body, Dementia with Lewy bodies, Mild cognitive impairment