Discover the most talked about and latest scientific content & concepts.

Journal: Minerva cardioangiologica


The effects of beta–blockers in pediatric and congenital heart disease (CHD) patients suffering from heart failure are controversial. We performed a meta–analysis to determine whether beta–blockers are effective for heart failure in pediatric and CHD patients.

Concepts: Medicine, Myocardial infarction, Hypertension, Cardiology, Heart failure


Transradial access has nowadays become a standard of care for percutaneous coronary angiography and intervention. This approach has demonstrated significant reduction in bleeding rate, length of hospital stay, and improvement in clinical outcomes when compared to the traditional transfemoral approach. Due to its advantages this new access is also increasingly being used in non-coronary visceral or peripheral interventions. However, this novel approach may lead to severe catheter kinking and twisting and further manipulation may be required to unravel the catheter and avoid complication. Purpose of this technical review is to present the current techniques and trends in preventing and resolving issues related to radial access catheter kinks.

Concepts: Present, Time, Atherosclerosis, Cardiology, Atheroma, Angiography, Intervention, The Current


Palliative care is an alternate therapeutic approach that involves specialized medical care of a patient diagnosed with serious life threatening illness like heart failure. The prime aim of the palliative care is to provide patient with relief from the symptoms, pain, physical stress, and mental stress of the diagnosed disease. The palliative care helps in improving the quality of life for both the patient and the family. Advanced heart failure (HF) is a disease process that carries a high burden of symptoms, suffering, and death. Palliative care can complement traditional care to improve symptom amelioration, patient–caregiver communication, emotional support, and medical decision making. The present review summarized all the available on alternative palliative approaches provided to heart patient by a team of physicians , nurses and other healthcare professionals.

Concepts: Health care, Medicine, Disease, Medical terms, Patient, Illness, Symptomatic treatment, Suffering


The efficacy of RADPAD ® (a sterile, lead–free drape) has been demonstrated to reduce the scatter radiation to the primary operator during fluoroscopic procedures. However, the use of the RADPAD ® during TAVI procedures has not been studied. Transcatheter Aortic Valve Implantation (TAVI) is now an established treatment for patients with symptomatic severe aortic stenosis who are deemed inoperable or at high risk for conventional surgical aortic valve replacement (AVR). Consequently the radiation exposure to the patient and the interventional team from this procedure has become a matter of interest and importance. Methods to reduce radiation exposure to the interventional team during this procedure should be actively investigated.

Concepts: Radiology, Aortic valve stenosis


Chronic increase in left ventricular filling pressure represents one of the most important mechanism underlying the structural, as well as the electrical, atrial chamber remodeling leading to atrial fibrillation. The present pilot pathophysiological study sought to investigate possible relationship between short–period cross–spectral coherence of P–Q, R–R and P–P intervals and echocardiographic indices of left ventricular and atrial function.

Concepts: Blood, Cardiology, Ejection fraction, Heart, Atrial fibrillation, Ventricle, Semitone, Jugular venous pressure


Coronary perforations (CP) have been described as a rare but potentially fatal complication in percutaneous coronary interventions (PCI). Our aim is to compare temporal trends in frequency, management and outcomes of coronary perforations (CP).

Concepts: Percutaneous coronary intervention


The aim of this study was to comprehensively determine haemodynamic and autonomic responses during-head up tilt test (HUT) in the acute and recovery phase of ischemic stroke.

Concepts: Blood vessel, Stroke, Thrombosis, Traumatic brain injury, Heart disease, Ischemia, Ischemic cascade, Embolism


Italy has been one of the first countries in Europe to perform primary percutaneous coronary intervention (p-PCI) and some regions are still a model for the ST-elevation myocardial infarction (STEMI) network organization. However, in Italy, as in other European countries, some regional disparities emerge that are related to geographical, economic, organizing, and structural issues. Although some regions have excellent STEMI networks, others still have to optimize their models allowing to each STEMI patient to receive the best reperfusion treatment. The RETE IMA Web surveys documented that extraordinary advances have been made in the recent past in Italy in development of STEMI networks, in part thanks to the activity of the Stent for Life project. Indeed, the current annual rate of p-PCI/million inhabitants in 2016 is quite compliant with the standards recommended from the European Society of Cardiology.

Concepts: Myocardial infarction, Atherosclerosis, Angina pectoris, Cardiology, Heart failure, Percutaneous coronary intervention, Atheroma, Europe


Reperfusion therapy of the infarct-related artery (IRA) with primary percutaneous coronary intervention (pPCI) is the cornerstone for the treatment of patients with ST-elevation myocardial infarction (STEMI). However, up to 30% of STEMI patients present a multi-vessel coronary artery disease. Several methods are now available for the assessment of functional severity of a coronary stenosis both for IRA and non culprit coronary lesions. The functional assessment of the IRA has mainly a prognostic implication in terms of major adverse cardiovascular events (MACEs), recovery of left ventricular function and evaluation myocardial viability. Conversely, the functional assessment of the non-culprit coronary lesions has a fundamental role to guide staged revascularization. The aim of this review is to revise the most validated methods to perform the functional assessment of both culprit and non-culprit lesion in ST-elevation myocardial infarction.

Concepts: Myocardial infarction, Atherosclerosis, Angina pectoris, Coronary artery disease, Heart, Atheroma, Cardiovascular system, Coronary artery bypass surgery


Acute myocardial infarction (AMI) is a major cause of morbidity, mortality and disability worldwide. ST-segment elevation myocardial infarction (STEMI) accounts for 25-40% of AMI presentations. Arterial thrombosis due to atherosclerotic plaque rupture with formation of an occlusive thrombus, is the main cause of STEMI . Platelets and coagulation factors are the two principal elements involved in this process. The main goal of STEMI treatment is the early reperfusion. Prompt primary percutaneous coronary intervention (pPCI) together with an appropriate antithrombotic therapy are the treatment of choice in this setting. In this chapter, we provide an overview of currently available parenteral antithrombotic therapies used in patients with STEMI undergoing pPCI.

Concepts: Blood, Myocardial infarction, Atherosclerosis, Cardiology, Stroke, Atheroma, Artery, Thrombus