Discover the most talked about and latest scientific content & concepts.

Journal: Minerva cardioangiologica


The effects of beta–blockers in pediatric and congenital heart disease (CHD) patients suffering from heart failure are controversial. We performed a meta–analysis to determine whether beta–blockers are effective for heart failure in pediatric and CHD patients.

Concepts: Medicine, Myocardial infarction, Hypertension, Cardiology, Heart failure


Transradial access has nowadays become a standard of care for percutaneous coronary angiography and intervention. This approach has demonstrated significant reduction in bleeding rate, length of hospital stay, and improvement in clinical outcomes when compared to the traditional transfemoral approach. Due to its advantages this new access is also increasingly being used in non-coronary visceral or peripheral interventions. However, this novel approach may lead to severe catheter kinking and twisting and further manipulation may be required to unravel the catheter and avoid complication. Purpose of this technical review is to present the current techniques and trends in preventing and resolving issues related to radial access catheter kinks.

Concepts: Present, Time, Atherosclerosis, Cardiology, Atheroma, Angiography, Intervention, The Current


Palliative care is an alternate therapeutic approach that involves specialized medical care of a patient diagnosed with serious life threatening illness like heart failure. The prime aim of the palliative care is to provide patient with relief from the symptoms, pain, physical stress, and mental stress of the diagnosed disease. The palliative care helps in improving the quality of life for both the patient and the family. Advanced heart failure (HF) is a disease process that carries a high burden of symptoms, suffering, and death. Palliative care can complement traditional care to improve symptom amelioration, patient–caregiver communication, emotional support, and medical decision making. The present review summarized all the available on alternative palliative approaches provided to heart patient by a team of physicians , nurses and other healthcare professionals.

Concepts: Health care, Medicine, Disease, Medical terms, Patient, Illness, Symptomatic treatment, Suffering


The efficacy of RADPAD ® (a sterile, lead–free drape) has been demonstrated to reduce the scatter radiation to the primary operator during fluoroscopic procedures. However, the use of the RADPAD ® during TAVI procedures has not been studied. Transcatheter Aortic Valve Implantation (TAVI) is now an established treatment for patients with symptomatic severe aortic stenosis who are deemed inoperable or at high risk for conventional surgical aortic valve replacement (AVR). Consequently the radiation exposure to the patient and the interventional team from this procedure has become a matter of interest and importance. Methods to reduce radiation exposure to the interventional team during this procedure should be actively investigated.

Concepts: Radiology, Aortic valve stenosis


Chronic increase in left ventricular filling pressure represents one of the most important mechanism underlying the structural, as well as the electrical, atrial chamber remodeling leading to atrial fibrillation. The present pilot pathophysiological study sought to investigate possible relationship between short–period cross–spectral coherence of P–Q, R–R and P–P intervals and echocardiographic indices of left ventricular and atrial function.

Concepts: Blood, Cardiology, Ejection fraction, Heart, Atrial fibrillation, Ventricle, Semitone, Jugular venous pressure


This registry study evaluated the effects of Pycnogenol® on edema and thrombotic complications in long-haul flights; jet lag was also evaluated.

Concepts: Jet airliner, Flight length, Great circle


Precise calcium evaluation in the aortic complex may be complicated. We aimed to assess the usefulness of a novel semi-automatic algorithm for multi slice computed tomography-derived (MSCT) quantitative estimation of aortic valve calcifications (AVC) in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI).


With the expanding indication of transcatheter aortic valve implantation (TAVI) to younger, lower risk population, transcatheter aortic valve (TAV) long-term durability is becoming an emerging issue to face with. Recently, the standardization of structural valve deterioration (SVD) definition by a join committee of the European Association of Percutaneous Cardiovascular Interventions (EAPCI), the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) has permitted to evaluate for the first time the rates of TAV durability with comparable endpoint. A few studies reporting on structural valve dysfunction (SVD) after TAVI up to 8 years using this standardized criteria have found very low rates of valve deterioration, thus supporting the adoption of TAVI treatment even for younger patients. For patients showing SVD at follow-ups, the VIVID (Valve-in-Valve International Data) group recently proposed an algorithm for their management. Re-do TAVI seems to be a safer and valid alternative to re-do surgery for symptomatic patients. This article review will go through the current evidence of TAV durability, describing the types of failure and strategies of treatment.


In this pilot non-interference clinical study we evaluated possible interactions between Quercetin Phytosome®, an innovative delivery form of quercetin, and antiplatelet agents, anticoagulants, and anti-diabetic therapy in otherwise healthy subjects.


The aim of the study was to assess safety TAVI procedure through the common carotid artery in high-vascular-risk patients.