Journal: Journal of affective disorders
200
The effects of vortioxetine on cognitive performance in working patients with major depressive disorder: A short-term, randomized, double-blind, exploratory study
- OPEN
- Journal of affective disorders
- Published about 1 year ago
- Discuss
Major Depressive Disorder (MDD) is a complex disease characterized by emotional, physical and cognitive symptoms. We explored the efficacy of vortioxetine versus placebo on outcomes of cognition, functioning and mood symptoms in working patients with depression, using paroxetine as an active reference.
77
A naturalistic examination of the perceived effects of cannabis on negative affect
- OPEN
- Journal of affective disorders
- Published 10 months ago
- Discuss
Cannabis is commonly used to alleviate symptoms of negative affect. However, a paucity of research has examined the acute effects of cannabis on negative affect in everyday life. The current study provides a naturalistic account of perceived changes in symptoms of depression, anxiety, and stress as a function of dose and concentration of Δ9tetrahydrocannabinol (THC) and cannabidiol (CBD).
55
Central bank interest rate decisions, household indebtedness, and psychiatric morbidity and distress: Evidence from the UK
- OPEN
- Journal of affective disorders
- Published 11 months ago
- Discuss
Central banks set economy-wide interest rates to meet exclusively economic objectives. There is a strong link between indebtedness and psychiatric morbidity at the individual level, with interest rates being an important factor determining ability to repay debt. However, no prior research has explored whether central bank interest rate changes directly influence mental health, nor whether this varies by levels of indebtedness.
45
Can smartphone mental health interventions reduce symptoms of anxiety? A meta-analysis of randomized controlled trials
- OPEN
- Journal of affective disorders
- Published almost 2 years ago
- Discuss
Various psychological interventions are effective for reducing symptoms of anxiety when used alone, or as an adjunct to anti-anxiety medications. Recent studies have further indicated that smartphone-supported psychological interventions may also reduce anxiety, although the role of mobile devices in the treatment and management of anxiety disorders has yet to be established.
40
The timing of general population and patient suicide in England, 1997-2012
- Journal of affective disorders
- Published almost 3 years ago
- Discuss
There have been conflicting findings on temporal variation in suicide risk and few have examined the phenomenon in clinical populations. The study investigated seasonal and other temporal patterns using national data.
38
Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo-controlled study
- Journal of affective disorders
- Published over 2 years ago
- Discuss
Several studies have supported the antidepressant effects of curcumin (from the spice turmeric) and saffron for people with major depressive disorder. However, these studies have been hampered by poor designs, small sample sizes, short treatment duration, and similar intervention dosages. Furthermore, the antidepressant effects of combined curcumin and saffron administration are unknown.
36
Vegetarian diets and depressive symptoms among men
- Journal of affective disorders
- Published over 1 year ago
- Discuss
Vegetarian diets are associate with cardiovascular and other health benefits, but little is known about mental health benefits or risks.
34
Internet-based versus face-to-face cognitive-behavioral intervention for depression: A randomized controlled non-inferiority trial
- Journal of affective disorders
- Published over 5 years ago
- Discuss
In the past decade, a large body of research has demonstrated that internet-based interventions can have beneficial effects on depression. However, only a few clinical trials have compared internet-based depression therapy with an equivalent face-to-face treatment. The primary aim of this study was to compare treatment outcomes of an internet-based intervention with a face-to-face intervention for depression in a randomized non-inferiority trial.
33
Investigation of short tandem repeats in major depression using whole-genome sequencing data
- Journal of affective disorders
- Published 12 months ago
- Discuss
Major depressive disorder (MDD) is a leading contributor to global disease burden. Recent studies have shown that genetic factors play significant roles in the susceptibility to this condition; however, the underlying genetic basis currently remains largely unknown. Short tandem repeat (STR) has been proposed as an explanatory factor in the “missing heritability” of complex diseases or traits.
32
Post-bereavement hallucinatory experiences: A critical overview of population and clinical studies
- Journal of affective disorders
- Published over 3 years ago
- Discuss
Removal of the “bereavement exclusion” criterion for major depression and proposed research criteria for persistent complex bereavement disorder in DSM-V pose new compelling issues regarding the adequacy of current nosographical boundaries. Post-bereavement hallucinatory experiences (PBHE) are abnormal sensory experiences that are frequently reported by bereaved individuals without a history of mental disorder. Given current uncertainty over the continuum of psychotic experiences in the general population, whether or not they should be considered pathological remains unclear.