Discover the most talked about and latest scientific content & concepts.

Journal: General hospital psychiatry


Neuroleptic malignant syndrome (NMS) is a rarely observed life-threatening medical condition due mostly to antipsychotic use. Additionally, a few case reports have suggested an association between NMS and the use of selective serotonin reuptake inhibitors (SSRIs) alone or in combination with antipsychotics. This case report presents a female patient developing NMS following the use of a combination of sertraline and paroxetine.

Concepts: Serotonin, Antidepressant, Selective serotonin reuptake inhibitor, Antipsychotic, Major depressive disorder, Sertraline, Fluoxetine, Neuroleptic malignant syndrome


Physicians have high rates of suicide and depression. Most state medical boards require disclosure of mental health problems on physician licensing applications, which has been theorized to increase stigma about mental health and prevent help-seeking among physicians.

Concepts: Medicine, Physician, Pediatrics, Mental disorder, Medical school, Specialty, Licensure, Hippocrates


Posttraumatic stress disorder (PTSD) is often underdiagnosed and undertreated among adolescents. The objective of this analysis was to describe the prevalence and correlates of symptoms consistent with PTSD among adolescents presenting to an urban emergency department (ED).

Concepts: Complex post-traumatic stress disorder, Posttraumatic stress disorder, Stress, Vietnam War


Patients with factitious disorder (FD) fabricate illness, injury or impairment for psychological reasons and, as a result, misapply medical resources. The demographic and clinical profile of these patients has yet to be described in a sufficiently large sample, which has prevented clinicians from adopting an evidence-based approach to FD. The present study aimed to address this issue through a systematic review of cases reported in the professional literature.

Concepts: Present, Medicine, Systematic review, Illness


To explore the reasons for worse cancer survival in people with experience of mental illness, including differences by cancer type and psychiatric diagnosis.

Concepts: Epidemiology, Mental health, Mental disorder, Psychiatry, Mental illness, Psychiatric hospital, Psychiatric medication, Cross-cultural psychiatry


Prior reviews evaluating the role of antidepressants in cancer-related depression have drawn conflicting conclusions. These reviews have also not explored differences in efficacy and tolerability between antidepressants. We conducted a meta-analysis to address these limitations.

Concepts: Evaluation, Evidence-based medicine, Systematic review, Review, Meta-analysis, Book review


To determine the 12-month cost-effectiveness of a collaborative care (CC) program for treating depression following coronary artery bypass graft (CABG) surgery versus physicians' usual care (UC).

Concepts: Atherosclerosis, Angina pectoris, Coronary artery disease, Randomized controlled trial, Artery, Coronary circulation, Coronary artery bypass surgery


To evaluate the prevalence and clinical correlates of metabolic syndrome (MetS) and its components among patients with psychiatric disorders.

Concepts: Psychology, Epidemiology, Cross-sectional study, Mental disorder, Psychiatry


Back pain (BP) is a leading cause of global disability. However, population-based studies investigating its impact on mental health outcomes are lacking, particularly among low- and middle-income countries (LMICs). Thus, the primary aims of this study were to: (1) determine the epidemiology of BP in 43 LMICs; (2) explore the relationship between BP and mental health (depression spectrum, psychosis spectrum, anxiety, sleep disturbances and stress).

Concepts: Psychology, Sleep, Sleep deprivation, Illness, Mental disorder, Positive psychology, Schizophrenia, Bipolar disorder


In the present study, we investigated individual differences in the outcome of patient-physician trust when confronted with cancer from an attachment theoretical perspective. We expected that lower levels of trust are associated with more emotional distress and more physical limitations within the first 15 months after diagnosis, especially in those who score relatively high on attachment anxiety. No such association was expected for more avoidantly attached individuals.

Concepts: Present, Time, Psychology, Medical diagnosis