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Journal: Cornea


To assess the effect of oral re-esterified omega-3 fatty acids on tear osmolarity, matrix metalloproteinase-9 (MMP-9), tear break-up time (TBUT), Ocular Surface Disease Index (OSDI), fluorescein corneal staining, Schirmer score, meibomian gland dysfunction (MGD) stage and omega-3 index in subjects with dry eyes and confirmed MGD.

Concepts: Eye, Essential fatty acid, Omega-6 fatty acid, Triglyceride, Meibomian gland, Nutrition, Omega-3 fatty acid, Fatty acid


: To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink.

Concepts: Inks, India ink, Ink


: To describe the incidence, characteristics, risk factors, treatment, and outcomes of ocular surface stem cell transplantation (OSST) rejection.

Concepts: Epidemiology, Organ transplant, Geometry


: To assess the effect of topical taprenepag isopropyl on each layer of the cornea by confocal microscopy.

Concepts: Optical sectioning, Microscopy, Confocal microscopy


: To assess the relationship between the thinnest corneal location and the steepest and maximum elevation corneal locations in subjects with keratoconus and the effect of gas permeable contact lens wear on the location of these points.

Concepts: Keratitis, Scleral lens, Orthokeratology, Lens, Contact lenses, Keratoconus, Cornea, Contact lens


: To report the beneficial properties of argon laser as an adjunctive therapy in 2 patients with refractory fungal keratitis.

Concepts: Keratitis, Argon, Laser


: To report the short-term visual outcomes and complications of keratoprosthesis surgery as the primary penetrating corneal procedure for patients at high risk for conventional corneal transplantation.

Concepts: Keratoprosthesis, Boston keratoprosthesis, Corneal transplantation, Ophthalmology


: Thygeson superficial punctate keratitis (TSPK), a chronic, inflammatory disease, has traditionally been taught to resolve spontaneously and without scarring. We present 4 cases with TSPK who developed sight-altering scarring after a prolonged disease course.

Concepts: Inflammation, Ophthalmology, Thygeson's superficial punctate keratopathy


PURPOSE:: To examine the agreement and relationship between refractive and corneal astigmatism in a population of pseudophakic eyes. METHODS:: Patients of age at least 40 years, visual acuity 20/40 or better, and no ocular disease were included (n = 111). Refractive astigmatism was obtained by subjective refraction. Corneal astigmatism was measured by automated keratometry and Scheimpflug scanning analysis. All refractive values were converted to power vector components J0 and J45 for comparison and regression analysis of refractive versus corneal astigmatism. Main outcome measures were refractive and corneal astigmatism components. RESULTS:: Median single Jackson cylinder (J) was similar in refractive [0.37 diopter (D)], keratometric (0.46 D), and Pentacam astigmatism (0.49 D) (P = 0.157). Median J0 astigmatic component was slightly negative, indicating against-the-rule (ATR) astigmatism, in refractive and Scheimpflug, but not in keratometric astigmatism (refractive J0: -0.10 D; keratometric J0: 0.05 D; Pentacam J0: -0.08 D) (P = 0.049). J45 astigmatic component was nearly zero and similar with the 3 methods (P = 0.416). Refractive and keratometric J0 were significantly correlated (r = 0.7, P < 0.01), as well as the corresponding J45 values (r = 0.65, P < 0.01). Refractive and Pentacam astigmatic components were worse correlated (J0: r = 0.36, P = 0.01; J45: r = 0.45, P < 0.01). Keratometric and Pentacam astigmatic components were also significantly correlated (J0: r = 0.58, P < 0.01; J45: r = 0.51, P < 0.01). CONCLUSIONS:: Mean internal ATR astigmatism, which comes mainly from the posterior corneal surface, adds to anterior corneal astigmatism, resulting in ATR refractive astigmatism. Correlation between refractive and corneal astigmatism components is better when keratometric data are used.

Concepts: Prediction interval, Lens, Visual acuity, Cornea, Refractive error, Astigmatism, Eye


To review an Acanthamoeba keratitis case series for the documented extracorneal spread of the amoeba.

Concepts: Keratitis, Amoeba, Amoebozoa, Amoeboid, Acanthamoeba