Discover the most talked about and latest scientific content & concepts.

Journal: Clinical oral investigations


The purpose of this study was to determine differences in effectiveness between two types of mandibular advancement device (MAD).

Concepts: Obstructive sleep apnea, Mandibular advancement splint


The authors analyzed the effect of fatigue on the survival rate and fracture load of monolithic and bi-layer CAD/CAM lithium-disilicate posterior three-unit fixed dental prostheses (FDPs) in comparison to the metal-ceramic gold standard.

Concepts: Fracture, Fracture mechanics, Gold, Gold standard


With direct and indirect digitalisation, two access points to CAD/CAM-generated restorations are available. The aim of this study was to compare the accuracy of the single steps of both approaches by comparing construction datasets using a new methodology.

Concepts: Comparison


The objective of this study is to develop a new approach for radiographically measuring circumferential periodontal bone level using cone beam CT (CBCT) data. Accuracy and precision were assessed using direct probe measurements on a human skull as a reference.

Concepts: Measurement, Psychometrics, Accuracy and precision, Helical cone beam computed tomography


Interleukin 8 (IL-8) is a pro-angiogenic, pro-inflammatory mediator that belongs to the family of chemokines. Due to its pro-angiogenic characteristic, it may play a vital role in tumour angiogenesis and progression.

Concepts: Inflammation, Cancer, Squamous cell carcinoma, Squamous epithelium, Chemokine, Interleukin 8, Interleukin 8 receptor, beta, Interleukin 8 receptor, alpha


The aim of this study was to compare two different thermoplastic techniques-a core-carrier technique (Thermafil) and warm vertical compaction-in terms of overextension of root canal filling in vivo.

Concepts: Comparison, In vivo, Creativity techniques, Comparisons


This randomized split-mouth clinical trial was designed to evaluate the efficacy of scaling and root planing associated to the high-intensity diode laser on periodontal therapy by means of clinical parameters and microbial reduction.

Concepts: Medicine, Clinical trial, Bacteria, Microbiology, Effectiveness,, Evaluation methods, Laser diode


OBJECTIVES: A selective intensified prevention (SIP) was introduced at individual schools in deprived areas in Marburg County (Germany) in 1995. The outcome of the program was evaluated in sixth graders (mean age: 12.06 years) in comparison to a control region. MATERIALS AND METHODS: Caries experience was recorded by applying International Caries Detection and Assessment System (ICDAS) II criteria. Tooth brushing habits and other independent variables were examined psychometrically. To compare the mean caries scores, non parametric tests were applied. The influence of various independent variables on caries experience was assessed by stepwise backward logistic regression analysis. The matching criteria age, gender, ethnicity and maternal education were used to parallelize the samples. RESULTS: ICDAS scores of 2-6 were detected uniformly more often in the control region than in the test group. Combining ICDAS scores 3-6, children from the control region (mean D(3-6)MFT: 1.73) showed roughly double the caries experience compared to the test group (mean D(3-6)MFT: 0.88, p < 0.005). The D(5,6)MFT score of the test group amounted to 0.50, and the corresponding value of the reference group was 0.77 (p = 0.043). Multivariate analysis disclosed fissure sealants, early start of tooth brushing and topical fluoride application to be associated with the prevention of dental caries. High frequency of sugar intake was associated with the presence of dentine lesions. CONCLUSIONS: The results of our study confirm the positive effect of SIP on the dental health of 12-year-old pupils living in deprived areas. CLINICAL RELEVANCE: On the basis of ICDAS II, targeted preventive measures can be applied in children with increased caries risk. Frequent applications of fluoride varnish inhibit the progression of initial lesions in this group.

Concepts: Regression analysis, Logistic regression, Statistics, Dental caries, Oral hygiene, Dental sealant, Fluoride therapy, Fluoride varnish


To investigate the temperature rise (TR) on the external root surface while preparing a staging platform, for removing intra-canal fractured instruments, using Gates Glidden (GG) drills.

Concepts: Trigraph, Gh


OBJECTIVE: This study aims to assess clinical, microbiological and inflammatory parameters as indicators for caries and periodontal disease in adolescents with obesity. MATERIAL AND METHODS: Twenty-seven adolescents with obesity [body mass index (BMI) 37 ± 4 kg/m(2)] and 28 controls (BMI 20 ± 2 kg/m(2)) answered questionnaires and were investigated regarding salivary parameters, plaque pH drop after a 1-min glucose rinse, oral clinical parameters, inflammatory markers in gingival crevicular fluid (GCF) and sub-gingival mirobiota. RESULTS: Compared with controls, adolescents with obesity had a lower stimulated salivary secretion rate (1.55 ± 0.63 vs. 2.05 ± 1.05 mL/min, p < 0.05), higher concentrations of secretory immunoglobulin A (sIgA) (p < 0.001), more decayed tooth surfaces (3.4 ± 6.6 vs. 0.8 ± 1.1, p < 0.05) and more gingivitis (p < 0.01) after controlling for possible confounders. Overall, similar snacking habits, plaque amounts and numbers of deep periodontal pockets were observed. Following the glucose rinse, a slightly more pronounced drop in plaque pH was observed in the obesity group (p > 0.05). No differences in sub-gingival inflammatory or microbial indicators were detected (p > 0.01). CONCLUSIONS: More caries and gingival inflammation were observed in adolescents with obesity. Of the indicators tested, salivary secretion rate was lower and sIgA levels were higher in the obesity group. We are unable to confirm whether differences in caries and gingival inflammation are due to systemic changes that are associated with obesity or due to possible irregular dietary/oral hygiene habits. CLINICAL RELEVANCE: Customised oral health preventive programmes and appropriate collaboration with medical personnel in selecting the best diet, medication and psychological support can help improve the general well-being, including oral health, of children with obesity. This may even reduce the risk of oral diseases.

Concepts: Immune system, Inflammation, Body mass index, Dental caries, Periodontitis, Periodontal disease, Dental plaque, Gingivitis