Discover the most talked about and latest scientific content & concepts.

Journal: Clinical case reports


Diabetes insipidus without perception of thirst, as may follow an anterior communicating artery aneurysm, requires prescription of fluid intake as well as desmopressin. The management goal of maintaining a normal serum sodium is rendered more challenging in a humid subtropical environment, where insensible losses are higher.

Concepts: Polydipsia, Durban, Management, Aneurysm, Earth, Diabetes insipidus, Anterior communicating artery, Climate


Methicillin-resistant Staphylococcus aureus (MRSA) infection is rapidly increasing in both hospital and community settings. A 71-year-old man admitted at the Department of Orthopaedics and Trauma Surgery, University Campus Bio-Medico of Rome, with MRSA wound infection consequent to orthopedic surgery was studied and the MRSA transmission evaluated by phylogenetic analysis.


Tea interferes with iron absorption and can lead to iron deficiency anemia when consumed in large quantities. The rechallenge effect of green tea on anemia in a middle-aged man emphasizes the potential causal role of this beverage. Lifestyle and dietary habits are important diagnostic considerations in diseases of this type.

Concepts: Iron, Death, Human iron metabolism, Transferrin, Hemoglobin, Iron deficiency anemia


This article is a case-report series showing the effectiveness of a three-month exposure to a synthetic analogue of Human Appeasing Pheromone as add-on strategy to psychopharmacological treatment on behavioral and residual symptoms of three patients suffering from severe psychiatric disorders with complex clinical pictures.

Concepts: Motivation, Species, Human behavior, Psychiatric medication, Behavior, Mental disorder, Psychiatry, Psychology


Despite a shift in clinical practice favouring cesarean section for breech presentation, adequate skills are still needed for a safe vaginal breech birth. This case report illustrates the physiological mechanism of vaginal breech birth. The accompanying pictures are a testimony to the “hands-off” approach and could be used for educational purposes.

Concepts: Obstetrics, Caesarean section, Breech birth, Childbirth


Bone marrow transplantation and stem cell therapies have been used for the treatment of common variable immunodeficiency (CVID) and other life-threatening medical disorders. This is the first known case report in the medical literature describing improvement of both Lyme disease and CVID with human embryonic stem cell therapy.


Capsule endoscopy was used to detect intestinal Taenia saginata infection in a 19-year-old man. The patient was initially believed to have Crohn’s disease due to a notable family history of the disease. Capsule endoscopy is a valuable tool for diagnosing tapeworm infection even when Crohn’s disease is suspected.

Concepts: Small intestine, Cestoda, Malabsorption, Colonoscopy, Ulcerative colitis, Taenia saginata, Crohn's disease, Gastroenterology


Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines.

Concepts: Immunology, Public health, Bacteria, Vaccine, Smallpox, Helicobacter pylori, Vaccination, Immune system


Ehlers-Danlos syndrome hypermobility type (EDS-HT) is an underdiagnosed genetic connective tissue disorder that causes joint hypermobility and widespread pain. We present a patient with the chief complaint of shoulder pain, a long history of widespread joint pain, and associated comorbidities. EDS-HT provided a unifying diagnosis and direction for management.

Concepts: Arthralgia, Medical terms, Syndromes, Collagen, Connective tissue, Hypermobility, Marfan syndrome, Ehlers-Danlos syndrome


Mutations in the SCN5A gene are linked to both the long QT syndrome 3 and Brugada syndrome with few reports describing an overlapping phenotype. We present a unique case and discuss clinical considerations of a patient concurrently exhibiting such conditions with genetic analysis confirming an SCN5A mutation.

Concepts: Cardiac electrophysiology, DNA, Sudden cardiac death, Long QT syndrome, Channelopathy, Evolution, Sodium channel, Syndromes