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Journal: Clinical and experimental otorhinolaryngology


Spontaneous nystagmus, which has been considered a typical sign of acute vestibulopathy, has recently been reported in benign paroxysmal positional vertigo involving the lateral semicircular canals (LC-BPPV) without unilateral vestibulopathy (pseudo-spontaneous nystagmus, PSN), but research about its clinical application is still limited. Here we investigate the frequency and characteristics of PSN in LC-BPPV patients, and estimate its prognostic value.

Concepts: Medical terms, Semicircular canal, Prognosis, Ear, Canal, Pathologic nystagmus, Benign paroxysmal positional vertigo, Horizontal semicircular canal


The clinical features of various facial deformities in Korean leprosy patients were evaluated according to the type of leprosy.

Concepts: According to Jim, Leprosy


Directional microphone technology can enhance the speech intelligibility and listening comfort of listeners with hearing impairment. The main aim of this study is to investigate and compare the benefit derived by listeners with severe hearing loss from directional microphone technology with that derived by listeners with moderate hearing loss.

Concepts: Sound, Audiogram, Hearing


This study compared the survival outcomes, local control rate, and laryngeal preservation rate of various treatment strategies in the treatment of T3 squamous cell carcinoma of the glottis using proportional meta-analyses.

Concepts: Carcinoma, Squamous cell carcinoma, Squamous epithelium, Meta-analysis, Glottis


Combined mastoidectomy is generally preferred to tympanoplasty alone when treating patients with chronic otitis media (COM), particularly when temporal bone computed tomography (TBCT) shows that the mastoid cavity contains opacification of soft tissue density. However, in cases with Eustachian tube dysfunction, a mastoid cavity volume may be a burden to its function. We hypothesized that tympanoplasty alone might be better than tympanoplasty combined with mastoidectomy because soft tissue in the mastoid cavity is a sequel to a protective physiological response. Thus, we explored the efficacy of tympanoplasty without mastoidectomy in COM patients exhibiting mastoid air cell opacification on TBCT.

Concepts: Sociology, Middle ear, Eustachian tube, Otitis media, Levator veli palatini, Bones of the head and neck, Patulous Eustachian tube


This study aimed to analyze the association between nutritional intake and tinnitus prevalence by evaluating a large cross-sectional cohort.

Concepts: Protein, Health, Epidemiology, Nutrition, Obesity, Fat, Diet, Dieting


Chronic otitis media (COM) is followed by irreversible tissue damage and destruction of the middle ear structures, with the possibility of complications under the maintenance of inflammation. Inflammatory mediators such as cytokines play a crucial role in the initial stage of inflammation. The aim of this study was to evaluate the association of the polymorphisms in two innate immunity/inflammation cascade genes from interleukin-1 (IL-1) gene cluster with COM with regard to cholesteatoma.

Concepts: Inflammation, Gene, Genetics, Allele, Middle ear, Otitis media, Ear, Debut albums


The pathophysiological mechanisms of chronic rhinosinusitis with nasal polyposis (CRSwNP) still are discussed controversially. Regulatory B cells (Breg) are responsible for the suppression of T cell activity: deficiencies for Breg have been demonstrated to contribute to autoimmune disorders, e.g., systemic lupus erythematosus. In order to evaluate the influence of B cell subpopulations, especially Breg, on the etiology of this disease, the aim of this study was to characterize subpopulations of peripheral and edaphic B cells in CRSwNP.

Concepts: Osteoporosis, Cell nucleus, Rheumatoid arthritis, Systemic lupus erythematosus, Lupus erythematosus, Headache


To investigate the short-term effects of a lifestyle modification intervention based on a mobile application (app) linked to a hospital electronic medical record (EMR) system on weight reduction and obstructive sleep apnea (OSA).

Concepts: Effect, Engineering, Sleep apnea, Obstructive sleep apnea, Electronic medical record, Personal digital assistant, Abnormal respiration


To examine the factors which affect the improvement or the recurrence of disease after intralesional steroid injection in patients with oral lichen planus (OLP).

Concepts: Affect, Lichen planus, Mucosal lichen planus