Discover the most talked about and latest scientific content & concepts.

Journal: BJOG : an international journal of obstetrics and gynaecology


To estimate the association between prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) and motor development in children considering the effect of maternal symptoms of anxiety and depression before, during and after pregnancy.

Concepts: Serotonin, Antidepressant, Selective serotonin reuptake inhibitor, Major depressive disorder, Sertraline, Tricyclic antidepressant, Reuptake inhibitor, Fluoxetine


To investigate the impact of prenatal antidepressant exposure on behavioural problems in children at 7 years of age.

Concepts: Child


To describe the incidence and nature of prenatal brain damage following fetoscopic laser selective coagulation (FLSC) of placental vessels for twin-to-twin transfusion syndrome (TTTS).

Concepts: Surgery, Obstetrics, Syndromes, Twin-to-twin transfusion syndrome, Multiple birth, Fetoscopy, Laser surgery, Polyhydramnios


Early reports of COVID-19 in pregnancy described management by caesarean, strict isolation of the neonate and formula feeding, is this practise justified?


The call for women-centred approaches to reduce labour interventions, particularly primary caesarean section, has renewed interest in a better understanding of natural labour progression.

Concepts: Childbirth, Obstetrics, Hysterectomy, Epidural, Caesarean section, Breech birth, Ventouse, Fetal distress


Cell-free fetal DNA (cffDNA) non-invasive prenatal testing (NIPT) is rapidly expanding, and is being introduced at varying rates depending on country and condition.

Concepts: Pregnancy, Embryo, Fetus, Uterus, Fertility, Abortion, Gestational age, Triple test


To investigate the effects of maternal and paternal depression on the risk for preterm birth.

Concepts: Cohort study, Childbirth, Mother


With changing conditions affecting receipt of postabortion care, an updated estimate of the incidence of treatment for complications from unsafe pregnancy termination is needed to inform policies and programmes. National estimates of facility-based treatment for complications in 26 countries form the basis for estimating treatment rates in the developing world. An estimated seven million women were treated in the developing world for complications from unsafe pregnancy termination in 2012, a rate of 6.9 per 1000 women aged 15-44 years. Regionally, rates ranged from 5.3 in Latin America and the Caribbean to 8.2 in Asia. Results inform policies to improve women’s health.

Concepts: United States, Approximation, Estimation, Americas


OBJECTIVE: To evaluate the effect of suggesting coitus as a safe and effective means to expedite labour on pregnancy duration and requirement for labour induction. DESIGN: A randomised trial. SETTING: Antenatal clinic in a university hospital in Malaysia. POPULATION: Women from 35 weeks of gestation with an uncomplicated singleton pregnancy. METHODS: The advise-coitus arm was counselled that coitus at term is a safe, natural and effective means to initiate labour and to avoid labour induction. The control arm was told coitus was safe. Both arms were asked to record coital activity. MAIN OUTCOME MEASURES: Pregnancy duration and labour induction. RESULTS: The intervention to delivery interval (mean ± SD) was 3.2 ± 1.4 versus 3.3 ± 1.3 weeks (P = 0.417), with a gestational age at delivery of 39.4 ± 1.2 versus 39.5 ± 1.2 weeks (P = 0.112), and with labour induction rates of 126/574 (22.0%) versus 120/576 (20.8%) (P = 0.666) for the advise-coitus and control arms, respectively, with no statistical difference between the groups. Coitus prior to delivery was more often reported in the advise-coitus arm compared with the control arm: 481/574 (85.3%) versus 458/576 (79.9%) (RR 1.5, 95% CI 1.1-2.0, P = 0.019). Also, the median (interquartile range) reported number of coital acts of 3 (2-5) versus 2 (1-4) (P = 0.006) was higher for the advise-coitus arm. Other pregnancy and neonatal outcomes did not differ between the groups. CONCLUSIONS: Labour onset and labour induction did not differ in the advise-coitus arm.

Concepts: Pregnancy, Childbirth, Embryo, Prenatal development, Fetus, Obstetrics, Gestation, Gestational age


What constitutes respectful maternity care (RMC) operationally in research and program implementation is often variable.

Concepts: Qualitative research