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Journal: Archives of gynecology and obstetrics

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To compare depressiveness scores, both during and after pregnancy, with the delivery mode (DM).

Concepts: Childbirth, Bipolar disorder, Postpartum depression, The Delivery

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To assess the need of episiotomy in a subsequent delivery in women with previous primiparous vaginal delivery with episiotomy.

Concepts: Childbirth

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The objective of this study is to describe a novel technique for the treatment of postpartum hemorrhage and evaluate its effectiveness and safety.

Concepts: Hemostasis, English-language films, Uterine atony

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Infection with Group B Streptococcus (GBS) is the most frequent in the first weeks of life of a newborn. The identification of pregnant women with GBS colonization may reduce neonatal infection.

Concepts: Pregnancy, Childbirth, Infant, Fetus, Streptococcus, Obstetrics, Breastfeeding, Streptococcus agalactiae

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PURPOSE: The production of reactive oxygen substances plays an important regulatory role in many physiologic reproductive processes. Excessive production may lead to oxidative stress (OS), and bring about pregnancy disorders. Growing evidence indicates that OS plays a major role in the pathophysiology of complications such as early pregnancy loss, placental insufficiency, preeclampsia, fetal growth restriction, and neonatal complications. Whether parturition induces oxidative stress is in dispute. In this review, we elaborate the influence of mode of delivery (vaginal delivery or cesarean delivery) on oxidative stress of neonates. METHODS: A review of old and recent literature was done. The studies were divided according to the impact of mode of delivery on oxidative stress in the newborn. RESULTS: There is a divergence in the oxidative stress production according to the mode of delivery. CONCLUSIONS: In view of neonatal oxidative stress measures, no major difference was found between uncomplicated vaginal delivery and elective cesarean section.

Concepts: Pregnancy, Childbirth, Infant, Fetus, Obstetrics, Caesarean delivery on maternal request, Abortion, Caesarean section

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BACKGROUND: 15 % of oocytes collected from Assisted Reproductive Technology (ART) cycles are immature. These oocytes may be matured following in vitro maturation (IVM) program. It is possible to cryopreserve the immature oocytes for further use in ART after application of IVM. OBJECTIVE: The aim was to determine the maturation rate and viability of human oocytes that were matured in vitro after vitrification program. MATERIALS AND METHODS: 63 women (19-43 years old) who underwent controlled ovarian stimulation for ART were included in this study. 53 immature oocytes were used for fresh group (fIVM) and 50 immature oocytes for vitrification group (vIVM). The maturation medium was Ham’s F10 supplemented with 0.75 IU FSH, 0.75 IU LH and 40 % human follicular fluid (HFF). After 36 h, maturation and morphology of all oocytes were assessed. Also, the oocyte viability was assessed using PI/Hoechst immunostaining technique. RESULTS: The maturation rates were reduced in vIVM group (56.0 %) in comparison to fIVM group (88.7 %; P < 0.001). Oocyte viability rate were also reduced in vIVM group (56.0 %) in comparison to fIVM (86.8 %, P < 0.007). CONCLUSIONS: Cryopreservation via vitrification reduced both the maturation capacity and viability of human oocytes in IVM technology. It is, therefore, recommended to apply IVM on fresh immature oocytes, instead.

Concepts: Reproduction, In vitro fertilisation, In vitro, Assisted reproductive technology, Oocyte, Cryobiology, Oocyte cryopreservation, Capacity

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OBJECTIVES: To test the effectiveness and safety of early amniotomy after vaginal misoprostol for the induction of labor. STUDY DESIGN: A randomized clinical trial that included 320 women with medical or obstetric indication for labor induction. They were randomly assigned into two equal groups, amniotomy group and control group. Each participant received vaginal misoprostol 50 μg every 6 h for induction of labor. In amniotomy group, amniotomy was done in the early active phase of labor while in the control group, the membranes were left to rupture spontaneously or as judged by the senior resident in the duty. RESULTS: More subjects in the amniotomy group achieved vaginal delivery within 24 h than in the control group [117 (73.13 %) vs. 105 (65.63 %)]. Subjects in the amniotomy group reported shorter induction to delivery interval (09.72 ± 4.61 h vs. 13.61 ± 5.61, P = .002), and better neonatal outcome compared to the control group. There were no statistically significant differences between both group with regard to number of doses of misoprostol, need for oxytocin, Cesarean Section indication and maternal side effects. CONCLUSION: Early amniotomy after vaginal misoprostol for labor induction is associated with higher successful vaginal delivery rate, shorter labor duration and better neonatal outcome.

Concepts: Childbirth, Clinical trial, Obstetrics, Oxytocin, Caesarean section, Labor induction, Pre-eclampsia, Misoprostol

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INTRODUCTION: The prevalence of bronchopulmonary dysplasia (BPD), one of the most frequently occurring complications following preterm birth, is increasing due to increased survival of preterm infants. METHODS: Systematic literature review. CONCLUSION: The etiology is multifactorial, with prematurity being a prerequisite for the development of BPD. Over time, there have been many different and new treatment modalities, some of them have reduced the severity of the disease, but none of them have been able to impact upon the increasing incidence of BPD.

Concepts: Childbirth, Epidemiology, Disease, Incidence, Prevalence, Preterm birth, Debut albums, Bronchopulmonary dysplasia

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PURPOSE: The role of thyroid function in biochemical markers of first trimester screening has not been assessed. The aim of the present study was to investigate if there were any relation between maternal thyroid hormones and free-beta subunit of human chorionic gonadotropin (fβ-hCG) and pregnancy-associated plasma protein A (PAPP-A) levels as the biochemical markers of the combined first trimester aneuploidy screening. METHODS: 375 pregnant women between 11 and 14 weeks of gestation who were offered routine first trimester prenatal aneuploidy screening and whose thyroid hormone levels (Thyroid stimulating hormone (TSH), free and total thyroxine, free and total triiodothyronine, anti thyroid peroxidase antibody) were measured were assessed. Correlation of free-β-hCG and PAPP-A with maternal thyroid hormones was analyzed. RESULTS: There was no statistically significant correlation between maternal TSH, free and total thyroxine, free and total triiodothyronine, anti-thyroid peroxidase antibodies and free-β-hCG and PAPP-A as biochemical markers of first trimester aneuploidy screening. CONCLUSION: Maternal thyroid function does not seem to affect secretion of fβ-hCG and PAPP-A.

Concepts: Pregnancy, Hormone, Thyroid, Thyroid hormone, Human chorionic gonadotropin, Triiodothyronine, Thyroxine, Thyroid peroxidase

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This study aims to investigate the impacts of CO2 pneumoperitoneum on the growth of ovarian cancer in nude mice and the expression of tumor metastasis suppressor gene (NM23-H1) and matrix metalloproteinase -2 (MMP-2) in SKOV-3 ovarian cancer cell line cancer tissue.

Concepts: Gene, Gene expression, Cell, Cancer, Metastasis, Oncology, BRCA2, Tumor suppressor gene