SciCombinator

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Concept: Recaldent

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Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and CPP-ACP with fluoride (CPP-ACFP) have been shown to provide bioavailable ions to promote mineralization. Hence, the aim of this study was to evaluate the materials' biocompatibility and osteogenic/calcification potential for endodontic applications.

Concepts: Milk, Calcium, Recaldent

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The study aimed to investigate the effects of bacterial biofilms on changes in the surface microhardness of enamel treated with casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) with and without fluoride. Human enamel blocks with incipient caries-like lesions were divided into four groups of 13: G1: Saliva (Control); G2: fluoride dentifrice (Crest™, 1100 ppm as NaF); G3: CPP-ACP (MI Paste; Recaldent™); and G4: CPP-ACPF (MI Paste Plus; Recaldent™ 900 ppm as NaF). The specimens were soaked in demineralizing solution for 6 h and remineralized in artificial saliva for 18 h alternately for 10 days. The dentifrice was prepared with deionized water in a 1 : 3 ratio (w/w) or applied undiluted in the case of the CPP-ACP group. The surface microhardness (SMH) was evaluated at baseline, after artificial caries, after pH cycling and treatment with dentifrices, and after incubation in media with Streptococcus mutans for biofilm formation. The biofilms were exposed once a day to 2% sucrose and the biofilm viability was measured by MTT reduction. The percentage of change in surface microhardness (%SMHC) was calculated for each block. The data were analyzed by nonparametric test comparisons (α = 0.05). The %SMHC values observed in G2 were different from those of G1, G3, and G4 (p < 0.05). After biofilm formation, %SMHC was positive in G2 and G4 when compared to G1 and G3, but resistance to demineralization after biofilm formation was similar in all groups. In conclusion, the presence of biofilms did not influence the treatment outcomes of anticaries products.

Concepts: Bacteria, Biofilm, Dental caries, Dental plaque, Tooth enamel, Remineralisation of teeth, Streptococcus mutans, Recaldent

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The purpose of this study was to evaluate the sensitivity of teeth with MIH in children before and after the use of a tooth mousse containing casein phosphopeptide and amorphous calcium phosphate (CPP-ACP).

Concepts: Milk, Calcium, Teeth, Tooth, Remineralisation of teeth, Recaldent

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To explore how application sequence of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride influences remineralization of enamel white spot lesions (WSL) in primary teeth.

Concepts: Milk, Calcium, Teeth, Tooth enamel, Recaldent

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Treatment of the cavity with silver diamine fluoride before placement of glass ionomer cement containing CPP-ACP enhances anticariogenic effect in vitro.

Concepts: Milk, Calcium, In vitro, Glass ionomer cement, Recaldent

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The objective of the present study is to evaluate the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on bleached enamel.

Concepts: Present, Milk, Calcium, Tooth enamel, Recaldent

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To evaluate the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) application on noncarious MIH (molar-incisor hypomineralisation) lesions by using a DIAGNOdent device (KaVo), which measures laser fluorescence within the mineral structure of the tooth.

Concepts: Bone, Milk, Calcium, Mineral, Fluorite, Fluoride, Calcium compounds, Recaldent

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To study the effect of silver diamine fluoride (SDF) treatment and incorporating casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) into a glass-ionomer cement (GIC) to prevent secondary caries.

Concepts: Milk, Prevention, Recaldent

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To evaluate the efficacy of minimally invasive methods for the treatment of white-spot lesions involving fluorides, CPP-ACP (casein phosphopeptide-stabilised amorphous calcium phosphate) and resin infiltration vs a placebo or control.

Concepts: Milk, Minimally invasive, Remineralisation of teeth, Recaldent