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Concept: Partial agonist


To determine safety and efficacy of the 5HT1A serotonin partial agonist buspirone on core autism and associated features in children with autism spectrum disorder (ASD).

Concepts: Randomized controlled trial, Autism, Agonist, Autism spectrum, 5-HT receptor, Buspirone, Partial agonist


Endoscopic band ligation (EBL) is used for primary (PP) and secondary prophylaxis (SP) of variceal bleeding. Current guidelines recommend combined use of non-selective beta-blockers (NSBBs) and EBL for SP, while in PP either NSBB or EBL should be used.

Concepts: Primary education, Beta blocker, Propranolol, Carvedilol, Partial agonist


Beta-blockers have become the treatment of choice for problematic infantile hemangiomas (IHs). Nadolol, a nonselective beta-blocker with potential dosing advantages and a better safety profile than that of other beta-blockers, has been studied as an alternative therapeutic option. Our objective was to characterize the efficacy and safety of oral nadolol in the treatment of proliferating IHs.

Concepts: Cohort study, Cohort, Cultural studies, Beta blocker, Beta blockers, Partial agonist, Nadolol


The anti-anginal efficacy of ivabradine is well established. We describe a post hoc analysis in the ADDITIONS database to investigate effectiveness and tolerability of ivabradine in combination with beta-blocker in patients with angina who have had a percutaneous coronary intervention (PCI).

Concepts: Myocardial infarction, Angina pectoris, Cardiology, Beta blocker, Post-hoc analysis, Partial agonist