Discover the most talked about and latest scientific content & concepts.

Concept: Keratomileusis


To evaluate clinical results of intrastromal corneal ring segments (ICRS) in a large series of post-laser in situ keratomileusis (LASIK) ectasia and determine which clinical parameters were related to the success of this technique.

Concepts: Carcinoma in situ, Laser, In situ, LASIK, Keratomileusis


Patient-reported outcomes should be collected using validated questionnaires prior to and following laser in situ keratomileusis (LASIK) surgery.

Concepts: Carcinoma in situ, Laser, Ophthalmology, In situ, LASIK, Keratomileusis


Laser in-situ keratomileusis (LASIK) is a commonly performed surgical procedure used to correct refractive error. LASIK surgery involves cutting a corneal flap and ablating the stroma underneath, with known damage to corneal nerves. Despite this, the epidemiology of persistent pain and other long-term outcomes after LASIK surgery are not well understood. Available data suggest that approximately 20-55% of patients report persistent eye symptoms (generally regarded as at least 6 months post-operation) after LASIK surgery. While it was initially believed that these symptoms were caused by ocular surface dryness, and referred to as “dry eye,” it is now increasingly understood that corneal nerve damage produced by LASIK surgery resembles the pathologic neuroplasticity associated with other forms of persistent post-operative pain. In susceptible patients, these neuropathological changes, including peripheral sensitization, central sensitization, and altered descending modulation, may underlie certain persistent dry eye symptoms after LASIK surgery. This review will focus on the known epidemiology of symptoms after LASIK and discuss mechanisms of persistent post-op pain due to nerve injury that may be relevant to these patients. Potential preventative and treatment options based on approaches used for other forms of persistent post-op pain and their application to LASIK patients are also discussed. Finally, the concept of genetic susceptibility to post-LASIK ocular surface pain is presented.

Concepts: Surgery, Laser, Cornea, Ophthalmology, Refractive surgery, LASIK, Keratoconus, Keratomileusis


To evaluate the safety of besifloxacin ophthalmic suspension 0.6% when used in laser-assisted in situ keratomileusis (LASIK) prophylactic antibiotic regimens.

Concepts: Carcinoma in situ, Retrospective, Ophthalmology, In situ, Refractive surgery, LASIK, Keratomileusis


To compare a biomechanically corrected intraocular pressure (bIOP) algorithm provided by the dynamic Scheimpflug analyzer (Corvis ST) with Goldmann applanation tonometry IOP (Goldmann IOP) and standard dynamic Scheimpflug analyzer IOP measurements before and after laser in situ keratomileusis (LASIK) and refractive lenticule extraction small-incision lenticule extraction (SMILE) surgeries.

Concepts: Laser, Intraocular pressure, Glaucoma, Ophthalmology, Tonometry, LASIK, Keratomileusis


To evaluate transient corneal tissue healing and biomechanical changes between laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) eyes.

Concepts: Laser, Eye, Cornea, In situ, LASIK, Keratomileusis


To evaluate the possible differences in visual quality between small incision lenticule extraction (SMILE) and femtosecond laser in situ keratomileusis (FS-LASIK) for myopia.

Concepts: Carcinoma in situ, Laser, Ophthalmology, In situ, Refractive surgery, LASIK, Keratomileusis


To study the relation between higher-order aberrations (HOAs) and contrast sensitivity (CS) in normal eyes among a population of laser in situ keratomileusis (LASIK) candidates.

Concepts: Carcinoma in situ, Laser, Ophthalmology, In situ, Refractive surgery, LASIK, Keratomileusis


To compare the astigmatism induced surgically (SIA) by spherical hyperopic laser in situ keratomileusis (H-LASIK) versus myopic laser in situ keratomileusis (M-LASIK) in nonastigmatic eyes.

Concepts: Laser, Ophthalmology, Myopia, Refractive surgery, Presbyopia, LASIK, Hyperopia, Keratomileusis


To report surgical management and favorable outcome in a case with delayed repair of traumatic laser in situ keratomileusis (LASIK) flap dislocation with shrinkage and folds.

Concepts: Carcinoma in situ, Surgery, Laser, Ophthalmology, In situ, LASIK, Keratomileusis