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Concept: Demographics of Japan


Several epidemiological studies have reported that high concentrations of circulating ferritin, a marker of iron stores, are related to insulin resistance (IR); however, questions remain regarding inconsistent data between Asian men and women and the inadequate consideration of potential confounding effects on the relationship between ferritin and IR. Our aim was to examine the relationship between serum ferritin concentrations and IR markers in the Japanese population.

Concepts: Japan, Iron deficiency anemia, Asia, Demographics of Japan


A meta-analysis showed an inverse association of a prudent/healthy dietary pattern with all-cause mortality and no association of a western/unhealthy dietary pattern. However, the association of distinctive dietary patterns of Japanese population with mortality remains unclear. We prospectively investigated the association between dietary patterns and all-cause, cancer, and cardiovascular disease mortality among Japanese adults.

Concepts: Epidemiology, Disease, Death, Demography, Japan, Ainu people, Japanese people, Demographics of Japan


Previous studies have shown that a diet with a high-glycemic index is associated with good sleep quality. Therefore, we investigated the association of sleep quality with the intake of 3 common starchy foods with different glycemic indexes-rice, bread, and noodles-as well as the dietary glycemic index in a Japanese population.

Concepts: Nutrition, The Association, Japan, Carbohydrate, Glycemic index, Diabetic diet, Potato, Demographics of Japan


Previous studies have suggested associations of family composition with morbidity and mortality; however, the evidence of associations with risk of stroke is limited. We sought to examine the impact of changes in the household composition on risk of stroke and its types in Japanese population. Cox proportional hazard modelling was used to assess the risk of incident stroke and stroke types within a cohort of 77,001 Japanese men and women aged 45-74 years who experienced addition and/or loss of family members [spouse, child(ren), parent(s) and others] to their households over a five years interval (between 1990-1993 and 1995-1998). During 1,043,446 person-years of the follow-up for 35,247 men and 41,758 women, a total of 3,858 cases of incident stroke (1485 hemorrhagic and 2373 ischemic) were documented. When compared with a stable family composition, losing at least one family member was associated with 11-15% increased risk of stroke in women and men; hazard ratios (95% confidence interval) were 1.11 (1.01-1.22) and 1.15 (1.05-1.26), respectively. The increased risk was associated with the loss of a spouse, and was evident for ischemic stroke in men and hemorrhagic stroke in women. The addition of any family members to the household was not associated with risk of stroke in men, whereas the addition of a parent (s) to the household was associated with increased risk in women: 1.49 (1.09-2.28). When the loss of a spouse was accompanied by the addition of other family members to the household, the increased risk of stroke disappeared in men: 1.18 (0.85-1.63), but exacerbated in women: 1.58 (1.19-2.10). In conclusion, men who have lost family members, specifically a spouse have higher risk of ischemic stroke, and women who gained family members; specifically a parent (s) had the higher risk of hemorrhagic stroke than those with a stable family composition.

Concepts: Family, Stroke, Japan, Household, The Loss, The Higher, Japanese people, Demographics of Japan


Post-micturition dribble (PMD) is one of the post-micturition lower urinary tract symptoms (LUTS). Although there have been many studies of LUTS in Japanese men, PMD is not completely understood in the Japanese population. In the present study, we investigated the prevalence and bother of PMD in Japanese men.

Concepts: Japan, Lower urinary tract symptoms, Demographics of Japan


The anterolateral ligament of the knee (ALL) has been attracting research attention as the ligament related to the Segond fracture. In this study, we investigated the prevalence and morphological variation of the ALL and developed a classification for the ALL in Japanese people.

Concepts: Japan, Asia, Bone fractures, Demographics of Japan


Due to ethic differences in its serum levels, clinical applicability of high-sensitivity C-reactive protein (hsCRP) to the primary prevention of atherosclerotic events has not completely been established in Japanese people whose hsCRP levels are lower than in Western people. This study investigated the relationship between hsCRP and myocardial infarction (MI) in general Japanese people.

Concepts: Myocardial infarction, Atherosclerosis, Cardiovascular disease, Stroke, Japan, Infarction, C-reactive protein, Demographics of Japan


Observational studies have reported that elevated homocysteine (Hcy) levels are associated with the risk of cardiovascular disease (CVD). However, interventions that lower Hcy do not provide a corresponding risk reduction. Therefore, the causal role of Hcy in CVD remains unclear. This 5-year prospective study investigated the associations of Hcy levels, folate intake, and host factors with arterial stiffness among the general Japanese population.

Concepts: Blood, Myocardial infarction, Cardiovascular disease, Japan, Folic acid, Asymmetric dimethylarginine, Homocysteine, Demographics of Japan


Uncertainty still surrounds the association between metabolic syndrome (MetS) and depression. We aimed to evaluate the association between MetS and elevated depressive symptoms in a general Japanese population.

Concepts: Life expectancy, Japan, Peru, Demographics of Japan


The effects of socio-economic factors on suicide were gender-dependent. Japanese suicide mortality gender ratio (male: female) had gradually increased during the twentieth century.

Concepts: Male, Female, Sexual dimorphism, Gender, Sex, Japan, Demographics of Japan, Suicide in Japan