SciCombinator

Discover the most talked about and latest scientific content & concepts.

Concept: Cortical homunculus

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PURPOSE: The purposes of this descriptive study were (a) to identify the relative frequencies of a priori categories of phantom limb pain (PLP) quality descriptors reported by Mid-Southerners with limb loss, (b) to analyze their descriptions for emerging categories of PLP, and © to identify the relative frequencies of the emerging categories. DESIGN: This cross-sectional descriptive verbal survey assessed PLP descriptors. A content analyses determined relative frequencies of a priori PLP descriptors as well as emerging categories that were identified. FINDINGS: The most common a priori PLP quality descriptors reported by 52 amputees with PLP were intermittent, tingling/needles/numb, sharp, cramping, burning, and stabbing. The most common emerging categories reported were pain compared to illness/injury, electrical cyclical, and manipulated/positional. CONCLUSION: The detailed descriptions of PLP provide insight into the vivid experiences of PLP. CLINICAL RELEVANCE: Rehabilitation nurses can use this information with PLP assessment, patient teaching, and counseling.

Concepts: Amputation, Proprioception, Phantom limb, Phantom pain, Illusion, Mirror box, Vilayanur S. Ramachandran, Cortical homunculus

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Post amputation, the complication of phantom limb pain (PLP) is prevalent and difficult to manage. This study aimed to determine whether it was feasible and acceptable to undertake a definitive multicentred randomised controlled trial assessing the effectiveness of acupuncture for treating lower limb amputees with PLP.

Concepts: Syndromes, Amputation, Proprioception, Phantom limb, Phantom pain, Mirror box, Vilayanur S. Ramachandran, Cortical homunculus

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We developed a quantitative method to measure movement representations of a phantom upper limb using a bimanual circle-line coordination task (BCT). We investigated whether short-term neurorehabilitation with a virtual reality (VR) system would restore voluntary movement representations and alleviate phantom limb pain (PLP).

Concepts: Scientific method, Upper limb, Virtual reality, Phantom limb, Phantom pain, Mirror box, Vilayanur S. Ramachandran, Cortical homunculus

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Cortical thickness has been investigated since the beginning of the 20th century, but we do not know how similar the cortical thickness profiles among humans are. In this study, the local similarity of cortical thickness profiles was investigated using sliding window methods. Here, we show that approximately 5% of the cortical thickness profiles are similarly expressed among humans while 45% of the cortical thickness profiles show a high level of heterogeneity. Therefore, heterogeneity is the rule, not the exception. Cortical thickness profiles of somatosensory homunculi and the anterior insula are consistent among humans, while the cortical thickness profiles of the motor homunculus are more variable. Cortical thickness profiles of homunculi that code for muscle position and skin stimulation are highly similar among humans despite large differences in sex, education, and age. This finding suggests that the structure of these cortices remains well preserved over a lifetime. Our observations possibly relativize opinions on cortical plasticity.

Concepts: Human, Cerebral cortex, Difference, 20th century, Human evolution, Cortical homunculus, Homo sapiens idaltu, Homunculus

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Cortex plasticity after hand amputation is considered harmful, causing phantom limb pain. A new study shows that cortical overtake can occur instead in a compensatory manner in people born with one hand, for multiple body parts used to overcome disability.

Concepts: Cerebral cortex, Amputation, Proprioception, Phantom limb, Phantom pain, Mirror box, Vilayanur S. Ramachandran, Cortical homunculus

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We utilized MRI to measure CBV in patients who had undergone unilateral arm amputation following electrical injury to investigate changes in the pain network associated with phantom limb pain.

Concepts: Amputation, Proprioception, Phantom limb, Phantom pain, Illusion, Mirror box, Vilayanur S. Ramachandran, Cortical homunculus

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To prospectively evaluate percutaneous image-guided nerve cryoablation for treatment of refractory phantom limb pain (PLP) in a pilot cohort for purposes of deriving parameters to design a larger, randomized, parallel-armed, controlled trial.

Concepts: Amputation, Proprioception, Phantom limb, Phantom pain, Illusion, Mirror box, Vilayanur S. Ramachandran, Cortical homunculus

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To determine the frequency of phantom limb sensation (PLS) and phantom limb pain (PLP) in children and young adults suffering landmine-related amputation.

Concepts: Amputation, Proprioception, Phantom limb, Phantom pain, Illusion, Mirror box, Vilayanur S. Ramachandran, Cortical homunculus