Discover the most talked about and latest scientific content & concepts.

Concept: Coronary circulation


Although some evidence shows that neighborhood deprivation is associated with greater subclinical atherosclerosis, prior studies have not identified what aspects of deprived neighborhoods were driving the association.

Concepts: Atherosclerosis, Atheroma, Artery, Coronary circulation


Diagnostic testing in the care of patients newly presenting with symptoms suggestive of coronary artery disease may influence risk factor management, independent of test type or test results. However, little is known about changes in medications and lifestyle after anatomical or functional testing.

Concepts: Medicine, Coronary artery disease, Artery, Coronary circulation


To investigate the association between regular coffee consumption and the prevalence of coronary artery calcium (CAC) in a large sample of young and middle-aged asymptomatic men and women.

Concepts: Artery, Coronary circulation


In patients with angina and nonobstructive coronary artery disease (NOCAD), confirming symptoms due to coronary microvascular dysfunction (CMD) remains challenging. Cardiac magnetic resonance (CMR) assesses myocardial perfusion with high spatial resolution and is widely used for diagnosing obstructive coronary artery disease (CAD).

Concepts: Myocardial infarction, Atherosclerosis, Angina pectoris, Coronary artery disease, Heart, Atheroma, Artery, Coronary circulation


Weaning from mechanical ventilation is a frequent nursing activity in critical care. Nature-based sound as a non-pharmacological and nursing intervention effective in other contexts may be an efficient approach to alleviating anxiety, agitation and adverse effects of sedative medication in patients undergoing weaning from mechanical ventilation.

Concepts: Clinical trial, Atherosclerosis, Coronary artery disease, Effect, Effectiveness, Artery, Coronary circulation, Coronary artery bypass surgery


There is limited contemporary data on achievement of risk factor goals for secondary prevention of cardiovascular (CV) disease from countries in many regions of the world. This report describes the global and regional prevalence of CV risk factors and use of preventive medications at baseline in participants in the ongoing STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY (STABILITY) trial.

Concepts: Epidemiology, Atherosclerosis, Heart, Risk, Atheroma, Heart disease, Artery, Coronary circulation


High-sensitivity cardiac troponin I (hs-cTnI) is a novel biomarker of myocardial injury and ischaemia. Our objective was to ascertain correlates of hs-cTnI and its incremental prognostic utility for incident coronary heart disease (CHD) among older asymptomatic subjects.

Concepts: Myocardial infarction, Heart, Cardiac muscle, Heart disease, Circulatory system, Artery, Coronary circulation, Troponin


Aspirin prevents coronary thrombosis and is used extensively in cardiovascular prophylaxis. However, patients with a prior history of an aspirin “reaction” are routinely denied this medication.

Concepts: Coronary artery disease, Heart, Artery, Coronary circulation, Cardiovascular system


To determine whether body mass index (BMI) and coronary artery calcification (CAC) are risk factors for kidney function decline in predialysis chronic kidney disease (CKD) patients.

Concepts: Chronic kidney disease, Kidney, Body mass index, Artery, Coronary circulation


Cardiac surgery patients are treated with antifibrinolytic agents to reduce intra- and postoperative bleeding. Until 2007, lysine analogues (aminocaproic acid and tranexamic acid) and serine protease inhibitors (aprotinin) were recommended. In 2008, the U.S. Food and Drug Administration prohibited aprotinin use because of associated postoperative complications, including cerebrovascular accidents and renal failure. This work aimed at reevaluating the efficacy and safety of aprotinin versus tranexamic acid in patients undergoing elective coronary artery bypass surgery.

Concepts: Atherosclerosis, Heart, Artery, Coronary circulation, Serine protease, Cardiovascular system, Coronary artery bypass surgery, Antifibrinolytics