SciCombinator

Discover the most talked about and latest scientific content & concepts.

Concept: Cardiomegaly

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-Left ventricular (LV) hypertrophy (LVH, high LV mass) is traditionally classified as concentric or eccentric based on LV relative wall thickness. We evaluated the prediction of subsequent adverse events in a new 4-group LVH classification based on LV dilatation (high LV end-diastolic volume [EDV] index) and concentricity (LVM/EDV((2/3))) in hypertensive patients.

Concepts: Hypertension, Cardiology, Left ventricular hypertrophy, Geometry, Ventricular hypertrophy, Aortic insufficiency, Cardiomegaly

2

Growth differentiation factor 11 and/or its homologue growth differentiation factor 8 (GDF11/8) reverses age-related cardiac hypertrophy and vascular ageing in mice. We investigated whether GDF11/8 associates with cardiovascular outcomes, left ventricular hypertrophy (LVH), or age in humans.

Concepts: Blood, Cardiology, Heart, Left ventricular hypertrophy, Circulatory system, Ventricular hypertrophy, Mitral valve, Cardiomegaly

0

Patients with hypertension with ECG left ventricular hypertrophy (LVH) have higher cardiovascular morbidity and mortality, but single ECG criteria may underestimate risk. Whether continued presence or new development of ECG LVH by 2 criteria can further concentrate risk during blood pressure lowering is unclear.

Concepts: Blood, Hypertension, Cardiology, Heart, Left ventricular hypertrophy, Ventricle, Ventricular hypertrophy, Cardiomegaly

0

High plasma concentration of fibroblast growth factor 23 (FGF23) is a risk factor for left ventricular hypertrophy (LVH) in adults with CKD, and induces myocardial hypertrophy in experimental CKD. We hypothesized that high FGF23 levels associate with a higher prevalence of LVH in children with CKD.

Concepts: Growth factor, Cardiology, Left ventricular hypertrophy, Chemistry, Fibroblast growth factor, Ventricular hypertrophy, Growth factors, Cardiomegaly

0

Frontal QRS-T angle is a novel marker of myocardial repolarization, and an increased frontal QRS-T angle associated with adverse cardiac outcomes. Non-dipper hypertension is also associated with adverse cardiac outcomes. This study aimed to investigate the relationship between frontal QRS-T angle and non-dipper status in hypertensive patients without left ventricular hypertrophy (LVH).

Concepts: Myocardial infarction, Hypertension, Cardiology, Heart, Left ventricular hypertrophy, Heart disease, Ventricular hypertrophy, Cardiomegaly

0

It is widely accepted that successful lowering of blood pressure (BP) in patients with hypertension leads to regression of left ventricular hypertrophy (LVH). However, whether differences exist among pharmacological BP-lowering therapies is debated. In this report, we discuss these differences in light of recent literature and the position of extant practice guidelines.

Concepts: Blood, Hypertension, Cardiology, Blood pressure, Left ventricular hypertrophy, Ventricle, Ventricular hypertrophy, Cardiomegaly

0

Left ventricular hypertrophy (LVH) is often encountered in clinical practice, and it is a risk factor for cardiac mortality and morbidity. Determination of the etiology and disease severity is important for the management of patients with LVH. The aim of this review is to show the remarkable progress in cardiac imaging and its importance in clinical practice.

Concepts: Epidemiology, Medical terms, Cardiology, The Canon of Medicine, Left ventricular hypertrophy, Ventricular hypertrophy, Differential diagnosis, Cardiomegaly

0

Data on left ventricular hypertrophy (LVH) in patients with renal artery stenosis (RAS) and its regression following renal revascularization are scanty. We performed a meta-analysis to provide comprehensive information on this clinically relevant issue.

Concepts: Kidney, Hypertension, Cardiology, Left ventricular hypertrophy, Ventricular hypertrophy, Renal artery, Renal artery stenosis, Cardiomegaly

0

Left ventricular hypertrophy (LVH) is very common in hemodialysis patients and an independent risk factor for mortality in this population. The myocardial remodeling underlying the LVH can affect ventricular repolarization causing abnormalities in QT interval.

Concepts: Cardiology, Left ventricular hypertrophy, Cardiac electrophysiology, QT interval, Psychometrics, Ventricular hypertrophy, Cardiomegaly

0

Electrocardiogram (ECG) is commonly used clinically due to convenience, but its accuracy is insufficient for left ventricular hypertrophy (LVH) diagnosis. In this study, we attempted to improve diagnostic accuracy of LVH by establishing models with ECG parameters.

Concepts: Cardiology, Left ventricular hypertrophy, Ventricular hypertrophy, Ventricular fibrillation, Electrocardiography, Cardiomegaly