SciCombinator

Discover the most talked about and latest scientific content & concepts.

Concept: Cardiomegaly

26

-Left ventricular (LV) hypertrophy (LVH, high LV mass) is traditionally classified as concentric or eccentric based on LV relative wall thickness. We evaluated the prediction of subsequent adverse events in a new 4-group LVH classification based on LV dilatation (high LV end-diastolic volume [EDV] index) and concentricity (LVM/EDV((2/3))) in hypertensive patients.

Concepts: Hypertension, Cardiology, Left ventricular hypertrophy, Geometry, Ventricular hypertrophy, Aortic insufficiency, Cardiomegaly

2

Growth differentiation factor 11 and/or its homologue growth differentiation factor 8 (GDF11/8) reverses age-related cardiac hypertrophy and vascular ageing in mice. We investigated whether GDF11/8 associates with cardiovascular outcomes, left ventricular hypertrophy (LVH), or age in humans.

Concepts: Blood, Cardiology, Heart, Left ventricular hypertrophy, Circulatory system, Ventricular hypertrophy, Mitral valve, Cardiomegaly

0

Long-term endurance sport practice leads to eccentric left ventricular hypertrophy (LVH). We aimed to compare the new 4-tiered classification (4TC) for LVH with the established 2-tiered classification (2TC) in a cohort of normotensive non-elite endurance athletes.

Concepts: Comparison, Cardiology, Heart, Left ventricular hypertrophy, Ventricular hypertrophy, Comparisons, Cardiomegaly

0

Impaired left atrial (LA) function is an early marker of cardiac dysfunction and predictor of adverse cardiac events. Herein, we assess LA structure and function in hypertrophy in hypertrophic cardiomyopathy (HCM) sarcomere mutation carriers with and without left ventricular hypertrophy (LVH).

Concepts: Blood, Cardiology, Cardiomyopathy, Heart, Left ventricular hypertrophy, Ventricular hypertrophy, Hypertrophic cardiomyopathy, Cardiomegaly

0

Left ventricular hypertrophy (LVH) is a predictor of mortality in hemodialysis. It takes a very high proportion among cardiovascular complications.

Concepts: Dialysis, Cardiology, Left ventricular hypertrophy, Hemodialysis, Ventricular hypertrophy, Exercise physiology, Cardiomegaly

0

Retinopathy and left ventricular hypertrophy (LVH) are representative markers of microvascular and cardiac dysfunction in patients with chronic kidney disease (CKD). However, their relationship and their combined effects on clinical outcomes are unknown.

Concepts: Chronic kidney disease, Kidney, Medicine, Hypertension, Cardiology, Left ventricular hypertrophy, Ventricular hypertrophy, Cardiomegaly

0

Patients with hypertension with ECG left ventricular hypertrophy (LVH) have higher cardiovascular morbidity and mortality, but single ECG criteria may underestimate risk. Whether continued presence or new development of ECG LVH by 2 criteria can further concentrate risk during blood pressure lowering is unclear.

Concepts: Blood, Hypertension, Cardiology, Heart, Left ventricular hypertrophy, Ventricle, Ventricular hypertrophy, Cardiomegaly

0

High plasma concentration of fibroblast growth factor 23 (FGF23) is a risk factor for left ventricular hypertrophy (LVH) in adults with CKD, and induces myocardial hypertrophy in experimental CKD. We hypothesized that high FGF23 levels associate with a higher prevalence of LVH in children with CKD.

Concepts: Growth factor, Cardiology, Left ventricular hypertrophy, Chemistry, Fibroblast growth factor, Ventricular hypertrophy, Growth factors, Cardiomegaly

0

Frontal QRS-T angle is a novel marker of myocardial repolarization, and an increased frontal QRS-T angle associated with adverse cardiac outcomes. Non-dipper hypertension is also associated with adverse cardiac outcomes. This study aimed to investigate the relationship between frontal QRS-T angle and non-dipper status in hypertensive patients without left ventricular hypertrophy (LVH).

Concepts: Myocardial infarction, Hypertension, Cardiology, Heart, Left ventricular hypertrophy, Heart disease, Ventricular hypertrophy, Cardiomegaly

0

It is widely accepted that successful lowering of blood pressure (BP) in patients with hypertension leads to regression of left ventricular hypertrophy (LVH). However, whether differences exist among pharmacological BP-lowering therapies is debated. In this report, we discuss these differences in light of recent literature and the position of extant practice guidelines.

Concepts: Blood, Hypertension, Cardiology, Blood pressure, Left ventricular hypertrophy, Ventricle, Ventricular hypertrophy, Cardiomegaly