Concept: Brotherhood of Evil
Given the important role of the brain in regulating endurance performance, this comparative study sought to determine whether professional road cyclists have superior inhibitory control and resistance to mental fatigue compared to recreational road cyclists.
Understanding how the brain works requires a delicate balance between the appreciation of the importance of a multitude of biological details and the ability to see beyond those details to general principles. As technological innovations vastly increase the amount of data we collect, the importance of intuition into how to analyze and treat these data may, paradoxically, become more important.
In neuroscience, as in many other scientific domains, the primary form of knowledge dissemination is through published articles. One challenge for modern neuroinformatics is finding methods to make the knowledge from the tremendous backlog of publications accessible for search, analysis and the integration of such data into computational models. A key example of this is metascale brain connectivity, where results are not reported in a normalised repository. Instead, these experimental results are published in natural language, scattered among individual scientific publications. This lack of normalisation and centralisation hinders the large-scale integration of brain connectivity results. In this paper, we present text-mining models to extract and aggregate brain connectivity results from 13.2 million PubMed abstracts and 630,216 full-text publications related to neuroscience. The brain regions are identified with three different named entity recognisers and then normalised against two atlases: the Allen Brain Atlas (ABA) and the atlas from the Brain Architecture Management System (BAMS). We then use three different extractors to assess inter-region connectivity.
Smith and Nichols discuss “big data” human neuroimaging studies, with very large subject numbers and amounts of data. These studies provide great opportunities for making new discoveries about the brain but raise many new analytical challenges and interpretational risks.
Computer models can make transcranial electric stimulation a better tool for research and therapy.
The consumption of fat is regulated by reward and homeostatic pathways, but no studies to our knowledge have examined the role of high-fat meal (HFM) intake on subsequent brain activation to oral stimuli.
To examine the effects of brief hypoxia (<7 min) due to cardiac arrest on the integrity of the brain and performance on memory and executive functions tasks.
Diet is a major issue facing humanity. To combat malnourishment and diseases associated with overnutrition, both research and technological breakthroughs are needed.
There is an increasing realization that the microorganisms which reside within our gut form part of a complex multidirectional communication network with the brain known as the microbiome-gut-brain axis. In this review, we focus on recent findings which support a role for this axis in modulating neurodevelopment and behavior.