Discover the most talked about and latest scientific content & concepts.

Concept: Bausch & Lomb


PURPOSE: To investigate differences in ocular aberrations induced by centre-near multifocal soft contact lenses (SCL) relative to single vision SCLs and their effect on contrast sensitivity function (CSF). METHODS: Ocular aberrometry was measured in 18 cyclopleged subjects (19-24 years) while wearing Ciba Air Optix low (AOlow) and high (AOhigh) add, Bausch & Lomb PureVision low (PVlow) and high (PVhigh) add multifocals, and a Bausch & Lomb PureVision single vision (PVsv) control with the same -3.00D distance back vertex power. Zernike polynomials were scaled to 4, 5 and 6mm pupils. CSF was measured at equivalent distances of 6m, 1m and 40cm while fully corrected with spherical trial lenses at 6m. RESULTS: AOlow, AOhigh and PVhigh induced a negative shift in primary spherical aberration (Z12) from PVsv and all multifocal SCLs induced a positive shift in secondary spherical aberration (Z24) (all p<0.01), without significantly increasing coma. Area under the CSF (AUCSF) reduced at 40cm for all multifocals relative to PVsv (p<0.05), but was not significantly different at 6m or 1m. A moderate correlation (r=-0.80, p<0.005) was found between changes in Z12 and AUCSF at 40cm for AOhigh, with an increase in negative Z12 reducing multifocal-induced loss of CSF. CONCLUSIONS: Centre-near multifocal SCLs induced a negative shift in Z12 and a positive shift in Z24. Although CSF was unaffected at 6m and 1m it was reduced at 40cm, possibly because changes in Z12 and Z24 were not great enough to induce a significant shift in centre of focus and increase in depth of field.

Concepts: Optics, Redox, Lens, Contact lens, Keratitis, Bausch & Lomb


There is increasing interest in fitting children with soft contact lenses. This review collates data from a range of studies to estimate the incidence of complications, specifically corneal infiltrative events and microbial keratitis, in patients under the age of 18 years.

Concepts: The Age, Cornea, Orthokeratology, Contact lens, Keratitis, Corneal ulcer, Bausch & Lomb


To report the observation of prolonged reepithelialization after photorefractive keratectomy (PRK) associated with the use of besifloxacin 0.6% (Besivance; Bausch & Lomb, Rochester, NY) underneath bandage contact lenses (BCLs) placed during surgery.

Concepts: Cornea, Contact lens, Keratitis, Photorefractive keratectomy, Rochester, New York, Bausch & Lomb, Bausch & Lomb Place, Mount Hope Cemetery, Rochester


To report the clinical outcomes of transscleral fixation using a single-piece foldable acrylic intraocular lens (IOL) with eyelets at the optic-haptic junction (enVista; Bausch & Lomb).

Concepts: Contact lens, Intraocular lens, Bausch & Lomb


To investigate the ability of protamine, alone or in combination with other antimicrobial agents, to kill bacteria and fungi associated with contact lens-related keratitis.

Concepts: Bacteria, Microbiology, Cornea, Contact lens, Keratitis, Corneal ulcer, Bausch & Lomb


We report a case of Acanthamoeba castellani keratitis in a person who wore contact lenses. The amebae hosted an ameba-resistant bacterial symbiont, provisionally named “Attilina massiliensis,” a yet undescribed α-Proteobacterium.

Concepts: Cornea, Contact lens, Keratitis, Corneal ulcer, Acanthamoeba, Bausch & Lomb


To present a case of diagnostic confusion in Nocardia keratitis in a contact lens wearer and to illustrate the characteristic clinical findings of this rare entity.

Concepts: Cornea, Myopia, Lens, Contact lens, Keratitis, Corrective lens, Corneal ulcer, Bausch & Lomb


To report a series of cases of Acanthamoeba keratitis (AK) in scleral lens wearers with keratoconus to determine whether this type of contact lens presents a greater risk for development of infection.

Concepts: Cornea, Contact lens, Contact lenses, Keratitis, Corneal ulcer, Keratoconus, Bausch & Lomb, Scleral lens


Acanthamoeba keratitis (AK) is a severe corneal infection that may occur as a serious outcome of improper use of contact lenses (CL).

Concepts: Cornea, Orthokeratology, Contact lens, Keratitis, Corneal ulcer, Egypt, Acanthamoeba, Bausch & Lomb


The purpose of this study was to develop a more efficient drug delivery device to overcome the limitations of current drop therapy for the treatment of fungal keratitis.

Concepts: Cornea, Myopia, Lens, Contact lens, Keratitis, Corrective lens, Corneal ulcer, Bausch & Lomb