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S Parajes, AO Chan, WM But, IT Rose, AE Taylor, V Dhir, W Arlt and N Krone
Abstract
Cytochrome P450 side-chain cleavage enzyme (CYP11A1) catalyses the first and rate-limiting step of steroidogenesis, the conversion of cholesterol to pregnenolone. CYP11A1 deficiency is commonly associated with adrenal insufficiency, and in 46,XY individuals, with variable degrees of disorder of sex development (DSD).
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Concepts
CYP17A1, Steroid, Testosterone, Cytochrome P450
MeSH headings
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