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Serum Hepcidin Is Associated With Presence of Plaque in Postmenopausal Women of a General Population

Arteriosclerosis, thrombosis, and vascular biology | 18 Dec 2013

TE Galesloot, S Holewijn, LA Kiemeney, J de Graaf, SH Vermeulen and DW Swinkels
Abstract
Iron and the iron regulatory hormone hepcidin, major determinant of body iron distribution, are hypothesized to play a role in cardiovascular disease. Here, we assess the associations of hepcidin as well as ferritin, iron, total iron-binding capacity, and transferrin saturation (ie, iron parameters) with noninvasive measurements of atherosclerosis in men and women of a population-based cohort.
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Concepts
Gender role, Blood vessel, Cardiovascular disease, Serum iron, Transferrin, Total iron-binding capacity, Transferrin saturation, Iron metabolism
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