OPEN BMC genomics | 12 Dec 2013
M Scotch, C Mei, YJ Makonnen, J Pinto, A Ali, S Vegso, M Kane, IN Sarkar and P Rabinowitz
Influenza A H5N1 has killed millions of birds and raises serious public health concern because of its potential to spread to humans and cause a global pandemic. While the early focus was in Asia, recent evidence suggests that Egypt is a new epicenter for the disease. This includes characterization of a variant clade 184.108.40.206, which has been found almost exclusively in Egypt.We analyzed 226 HA and 92 NA sequences with an emphasis on the H5N1 220.127.116.11 strains in Egypt using a Bayesian discrete phylogeography approach. This allowed modeling of virus dispersion between Egyptian governorates including the most likely origin.
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