Loss of id3 increases vcam-1 expression, macrophage accumulation, and atherogenesis in ldlr-/- mice.
Arteriosclerosis, thrombosis, and vascular biology | 9 Oct 2012
MJ Lipinski, KA Campbell, SQ Duong, TJ Welch, JC Garmey, AC Doran, MD Skaflen, SN Oldham, KA Kelly and CA McNamara
Inhibitor of differention-3 (Id3) promotes B cells homing to the aorta and atheroprotection in Apoe(-/-) mice. We sought to determine the impact of loss of Id3 in the Ldlr((-/-)) mouse model of diet-induced atherosclerosis and identify novel Id3 targets in the vessel wall.
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