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N Zippel, RA Malik, T Frömel, R Popp, E Bess, B Strilic, N Wettschureck, I Fleming and B Fisslthaler
Abstract
Transforming growth factor-β-activated kinase 1 (TAK1) is a mitogen-activated protein 3-kinase and an AMP-activated protein kinase (AMPK) kinase in some cell types. Although TAK1(-/-) mice display defects in developmental vasculogenesis, the role of TAK1 in endothelial cells has not been investigated in detail.
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Concepts
Protein kinase A, Endothelium, Protein kinases, Signal transduction, Gene, Angiogenesis, Enzyme, Adenosine triphosphate
MeSH headings
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