Minerva ginecologica | 12 Dec 2020
A La Marca, M Capuzzo, MG Imbrogno, V Donno, G Spedicato, S Sacchi, MG Minasi, F Spinella, P Greco, F Fiorentino and E Greco
Female age is the strongest predictor of embryo chromosomal abnormalities and has a non linear relationship with the blastocyst euploidy rate: with advancing age there is an acceleration in the reduction of blastocyst euploidy. Aneuploidy was found to significantly increase with maternal age from 30% in embryos from young women to 70% in women older than 40 years old. The association seems mainly due to chromosomal abnormalities occurring in the oocyte.We aimed to elaborate a model for the blastocyst euploid rate for patients undergoing IVF/ICSI cycles using advanced machine learning techniques.
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