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An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

OPEN The New England journal of medicine | 15 Jul 2020

LA Jackson, EJ Anderson, NG Rouphael, PC Roberts, M Makhene, RN Coler, MP McCullough, JD Chappell, MR Denison, LJ Stevens, AJ Pruijssers, A McDermott, B Flach, NA Doria-Rose, KS Corbett, KM Morabito, S O'Dell, SD Schmidt, PA Swanson, M Padilla, JR Mascola, KM Neuzil, H Bennett, W Sun, E Peters, M Makowski, J Albert, K Cross, W Buchanan, R Pikaart-Tautges, JE Ledgerwood, BS Graham and JH Beigel
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally, prompting an international effort to accelerate development of a vaccine. The candidate vaccine mRNA-1273 encodes the stabilized prefusion SARS-CoV-2 spike protein.
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