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S Bouri, MJ Shun-Shin, GD Cole, J Mayet and DP Francis
Abstract
Current European and American guidelines recommend the perioperative initiation of a course of β-blockers in those at risk of cardiac events undergoing high- or intermediate-risk surgery or vascular surgery. The Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography (DECREASE) family of trials, the bedrock of evidence for this, are no longer secure. We therefore conducted a meta-analysis of randomised controlled trials of β-blockade on perioperative mortality, non-fatal myocardial infarction, stroke and hypotension in non-cardiac surgery using the secure data.
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Concepts
Ejection fraction, Stroke, Hypertension, Atherosclerosis, Epidemiology, Randomized controlled trial, Myocardial infarction, Cardiology
MeSH headings
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