Indications for extrahepatic bile duct resection due to perineural invasion in patients with gallbladder cancer
OPEN World journal of surgical oncology | 2 Dec 2019
S Maruyama, H Kawaida, N Hosomura, H Amemiya, R Saito, H Shimizu, S Furuya, H Akaike, Y Kawaguchi, M Sudo, S Inoue, H Kono and D Ichikawa
The indications for extrahepatic bile duct (EHBD) resection remain a major controversy in the surgical management of patients with gallbladder cancer. On the other hand, perineural invasion (PNI) was reported as an important factor in patients with gallbladder cancer because gallbladder cancer cells frequently spread to the tissues surrounding the EHBD via perineural routes. We assessed the correlation of PNI with clinicopathological factors in patients with gallbladder cancer to elucidate EHBD resection indications specifically in patients with PNI.
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