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Thyroid hormone and folinic acid in young children with Down syndrome: the phase 3 ACTHYF trial

Genetics in medicine : official journal of the American College of Medical Genetics | 10 Jul 2019

C Mircher, S Sacco, C Bouis, J Gallard, A Pichot, E Le Galloudec, C Cieuta, I Marey, O Greiner-Mahler, N Dorison, A Gambarini, S Stora, S Durand, M Polak, A Baruchel, E Schlumberger, J Dewailly, A Azar-Kolakez, RM Guéant-Rodriguez, JL Guéant, D Borderie, D Bonnefont-Rousselot, E Blondiaux, A Ravel and FG Sturtz
Abstract
To determine whether folinic acid (FA) and thyroxine, in combination or alone, benefit psychomotor development in young patients with Down syndrome (DS).
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