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X Zhang, W Qiu, X Ma, J Evans, M Kaur, JP Jasinski and W Zhang
Abstract
Sequential inter- and intramolecular [3+2] cycloadditions of azomethine ylides is developed for one-pot and diastereoselective synthesis of highly condensed heterocyclic systems containing pyrrolidine and up to seven stereocenters. It has high synthetic efficiency, operational simplicity, and only water was generated as a byproduct.
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