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Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing

OPEN The New England journal of medicine | 4 Oct 2018

Abstract
The World Health Organization recommends drug-susceptibility testing of Mycobacterium tuberculosis complex for all patients with tuberculosis to guide treatment decisions and improve outcomes. Whether DNA sequencing can be used to accurately predict profiles of susceptibility to first-line antituberculosis drugs has not been clear.
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