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CE Wilshire, T Kindlon, R Courtney, A Matthees, D Tuller, K Geraghty and B Levin
Abstract
The PACE trial was a well-powered randomised trial designed to examine the efficacy of graded exercise therapy (GET) and cognitive behavioural therapy (CBT) for chronic fatigue syndrome. Reports concluded that both treatments were moderately effective, each leading to recovery in over a fifth of patients. However, the reported analyses did not consistently follow the procedures set out in the published protocol, and it is unclear whether the conclusions are fully justified by the evidence.
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Concepts
Report, Semitone, Randomized controlled trial, Chronic fatigue syndrome, Cognitive behavioral therapy
MeSH headings
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