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Mild Cognitive Impairment in Parkinson’s Disease-What Is It?

OPEN Current neurology and neuroscience reports | 12 Mar 2018

RS Weil, AA Costantini and AE Schrag
Abstract
Mild cognitive impairment is a common feature of Parkinson’s disease, even at the earliest disease stages, but there is variation in the nature and severity of cognitive involvement and in the risk of conversion to Parkinson’s disease dementia. This review aims to summarise current understanding of mild cognitive impairment in Parkinson’s disease. We consider the presentation, rate of conversion to dementia, underlying pathophysiology and potential biomarkers of mild cognitive impairment in Parkinson’s disease. Finally, we discuss challenges and controversies of mild cognitive impairment in Parkinson’s disease.
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Concepts
Dementia, Parkinson's disease, Alzheimer's disease
MeSH headings
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