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BLAST: a more efficient report with usability improvements

OPEN Nucleic acids research | 24 Apr 2013

GM Boratyn, C Camacho, PS Cooper, G Coulouris, A Fong, N Ma, TL Madden, WT Matten, SD McGinnis, Y Merezhuk, Y Raytselis, EW Sayers, T Tao, J Ye and I Zaretskaya
Abstract
The Basic Local Alignment Search Tool (BLAST) website at the National Center for Biotechnology (NCBI) is an important resource for searching and aligning sequences. A new BLAST report allows faster loading of alignments, adds navigation aids, allows easy downloading of subject sequences and reports and has improved usability. Here, we describe these improvements to the BLAST report, discuss design decisions, describe other improvements to the search page and database documentation and outline plans for future development. The NCBI BLAST URL is http://blast.ncbi.nlm.nih.gov.
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Concepts
Searching, Smith–Waterman algorithm, Dynamic programming, Bioinformatics, FASTA, Sequence alignment, Computational phylogenetics, BLAST
MeSH headings
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