Effect of increased time in the therapeutic range on atrial fibrillation outcomes within a centralized anticoagulation service
Thrombosis research | 7 Feb 2018
E Phelps, T Delate, DM Witt, PB Shaw, KH McCool and NP Clark
Clinical pharmacy anticoagulation services have improved the quality of anticoagulant therapy and are associated with lower rates of bleeding and thromboembolism compared to usual care. Several studies have found that higher time-in-therapeutic range (TTR) during warfarin therapy is associated with better warfarin outcomes. However, whether increasing TTR over time within an established anticoagulation service is associated with further reduction in bleeding and thromboembolic outcomes is unknown.
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