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M García-Ramírez, M Turch, O Simó-Servat, C Hernández and R Simó
Abstract
Vascular endothelial growth factor (VEGF) plays an essential role in development of diabetic macular edema (DME). While there is evidence suggesting that silymarin, a flavonoid extracted from Silybum marianum, could be useful for prevention and treatment of diabetic nephropathy, no studies have been conducted in diabetic retinopathy (DR). The aim of this study was to assess the effect of silymarin on disruption of inner blood retinal barrier (BRB), the primary cause of DME.
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Concepts
Macular edema, Diabetes mellitus, Angiogenesis, Ophthalmology, Silybum marianum, Retina, Vascular endothelial growth factor, Diabetic retinopathy
MeSH headings
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