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A Rickli, E Liakoni, MC Hoener and ME Liechti
Abstract
Opioids may inhibit the serotonin and norepinephrine transporters (SERT and NET, respectively). NET inhibition may contribute to analgesia, and SERT inhibition or interactions with serotonin receptors may cause serotonergic toxicity. However, the effects of different opioids on the human SERT, NET, and serotonin receptors have not been sufficiently studied.
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Concepts
Inhibitor, Pharmacology, 5-HT receptor, Pethidine, Tramadol, Norepinephrine, Antidepressant, Serotonin
MeSH headings
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