Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease
OPEN The Korean journal of internal medicine | 28 Nov 2017
SH Baek, RH Cha, SW Kang, CW Park, DR Cha, SG Kim, SA Yoon, S Kim, SY Han, JH Park, JH Chang, CS Lim, YS Kim and KY Na
Patients with chronic kidney disease (CKD) have been found to show markedly increased rates of end-stage renal disease, major adverse cardiovascular and cerebrovascular events (MACCEs), and mortality. Therefore, new biomarkers are required for the early detection of such clinical outcomes in patients with CKD. We aimed to determine whether the level of circulating renalase was associated with CKD progression, MACCEs, and all-cause mortality, using data from a prospective randomized controlled study, Kremezin STudy Against Renal disease progression in Korea (K-STAR; NCT 00860431).
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