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From specific Humidifier disinfectants disease to Humidifier disinfectants syndrome

OPEN Environmental health and toxicology | 14 Oct 2017

JH Leem and JH Lee
Abstract
Humidifier disinfectant damage was terrible chemical damage caused by household goods that happened in only South Korea, but it is still very little known in humidifier disinfectant damage. Up to now, previous research tried to focus on interstitial fibrosis on terminal bronchiole and alveoli because it is specific finding, compared with other diseases. To figure out overall effects from HDs, many epidemiologic and toxicologic research is underway. Humidifier disinfectants showed to give rise to typical toxicologic effects on various target organs, such as skin, conjunctiva, naval mucosa, bronchial mucosa, alveoli and so on, which were sharing common toxicological responses. On specific target, specific toxicologic effects existed. Diverse diseases along exposure pathways can occur at the same time with common toxicologic mechanism and cause of humidifier disinfectants, which can be called as humidifier disinfectants syndrome. To gain more strong scientific evidence about it, further epidemiological and toxicological studies should be applied.
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Concepts
Research, Demography, Cancer, Bronchiole, Scientific method, Infectious disease, Disease, Epidemiology
MeSH headings
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