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TJ Cheng, SY Wang, WH Wen, CY Su, M Lin, WI Huang, MT Liu, HS Wu, NS Wang, CK Cheng, CL Chen, CT Ren, CY Wu, JM Fang, YS Cheng and CH Wong
Abstract
The wizard of OS (resistance): The binding difference of neuraminidase inhibitors (zanamivir versus oseltamivir (OS)) was used to establish an assay to identify the influenza subtypes that are resistant to OS but still sensitive to zanamivir. This assay used a zanamivir-biotin conjugate to determine the OS susceptibility of a wide range of influenza viruses and over 200 clinical isolates.
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Concepts
Antibiotic resistance, Antiviral drug, Zanamivir, Neuraminidase inhibitor, Viral neuraminidase, Oseltamivir, Influenza, Neuraminidase
MeSH headings
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