SciCombinator

Discover the most talked about and latest scientific content & concepts.

I Schreiver, B Hesse, C Seim, H Castillo-Michel, J Villanova, P Laux, N Dreiack, R Penning, R Tucoulou, M Cotte and A Luch
Abstract
The increasing prevalence of tattoos provoked safety concerns with respect to particle distribution and effects inside the human body. We used skin and lymphatic tissues from human corpses to address local biokinetics by means of synchrotron X-ray fluorescence (XRF) techniques at both the micro (μ) and nano (ν) scale. Additional advanced mass spectrometry-based methodology enabled to demonstrate simultaneous transport of organic pigments, heavy metals and titanium dioxide from skin to regional lymph nodes. Among these compounds, organic pigments displayed the broadest size range with smallest species preferentially reaching the lymph nodes. Using synchrotron μ-FTIR analysis we were also able to detect ultrastructural changes of the tissue adjacent to tattoo particles through altered amide I α-helix to β-sheet protein ratios and elevated lipid contents. Altogether we report strong evidence for both migration and long-term deposition of toxic elements and tattoo pigments as well as for conformational alterations of biomolecules that likely contribute to cutaneous inflammation and other adversities upon tattooing.
Tweets*
377
Facebook likes*
49
Reddit*
2
News coverage*
107
Blogs*
13
SC clicks
1
Concepts
Heavy metal music, Tissue, Lymphatic system, Lymph node, Tattoo, Oxygen, Skin, Titanium dioxide
MeSH headings
-
comments powered by Disqus

* Data courtesy of Altmetric.com