OPEN Journal of psychopharmacology (Oxford, England) | 26 Jul 2017
L Koenders, V Lorenzetti, L de Haan, C Suo, W Vingerhoets, W van den Brink, RW Wiers, CJ Meijer, M Machielsen, AE Goudriaan, DJ Veltman, M Yücel and J Cousijn
Cannabis exposure, particularly heavy cannabis use, has been associated with neuroanatomical alterations in regions rich with cannabinoid receptors such as the hippocampus in some but not in other (mainly cross-sectional) studies. However, it remains unclear whether continued heavy cannabis use alters hippocampal volume, and whether an earlier age of onset and/or a higher dosage exacerbate these changes.
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