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M Nilforoushzadeh, E Rahimi Jameh, F Jaffary, E Abolhasani, G Keshtmand, H Zarkob, P Mohammadi and N Aghdami
Abstract
Dermal papilla and hair epithelial stem cells regulate hair formation and the growth cycle. Damage to or loss of these cells can cause hair loss. Although several studies claim to reconstitute hairs using rodent cells in an animal model, additional research is needed to develop a stable human hair follicle reconstitution protocol. In this study, we have evaluated hair induction by injecting adult cultured human dermal papilla cells and a mixture of hair epithelial and dermal papilla cells in a mouse model.
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Concepts
Animal model, Rodent, Skin, Mouse, Long hair, Protein, Hair follicle, Hair
MeSH headings
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