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T Kiguradze, WH Temps, PR Yarnold, J Cashy, RE Brannigan, B Nardone, G Micali, DP West and SM Belknap
Abstract
Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers' full prescribing information (FPI) for finasteride and dutasteride state that risk of sexual adverse effects is not increased by longer duration of 5α-RI exposure and that sexual adverse effects of 5α-RIs resolve in men who discontinue exposure.
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102
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6
Concepts
Exposure, ClinicalTrials.gov, Clinical trial, Effectiveness, Adverse drug reaction, Erectile dysfunction, Pharmaceutical industry
MeSH headings
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