SciCombinator

Discover the most talked about and latest scientific content & concepts.

Memantine Induces NMDAR1-Mediated Autophagic Cell Death in Malignant Glioma Cells

OPEN Journal of Korean Neurosurgical Society | 8 Mar 2017

WS Yoon, MY Yeom, ES Kang, YA Chung, DS Chung and SS Jeun
Abstract
Autophagy is one of the key responses of cells to programmed cell death. Memantine, an approved anti-dementia drug, has an antiproliferative effect on cancer cells but the mechanism is poorly understood. The aim of the present study was to test the possibility of induction of autophagic cell death by memantine in glioma cell lines.
Tweets*
0
Facebook likes*
0
Reddit*
0
News coverage*
1
Blogs*
0
SC clicks
0
Concepts
Glioma, Cell division, Brain tumor, Apoptosis, Cancer, Oncology, Metastasis, Programmed cell death
MeSH headings
-
comments powered by Disqus

* Data courtesy of Altmetric.com