SciCombinator

Discover the most talked about and latest scientific content & concepts.

Hedgehog Pathway Inhibitors - Current Status and Future Prospects.

OPEN Infectious agents and cancer | 3 Nov 2012

A Sheikh, AA Alvi, HM Aslam and A Haseeb
Abstract
The Hedgehog (Hh) proteins comprise a group of secreted proteins that regulate cell growth, differentiation and survival. Inappropriate activation of the Hh signaling pathway has been implicated in the development of a variety of cancers. Hh pathway inhibitors are a relatively new class of therapeutic agents that act by targeting the proteins involved in the regulation of Hh pathway (PTCH, SMO and Gli). Together, they serve as exciting new prospects, with a bright future, both alone or as an adjuvant to the more traditional anti-cancer drugs.
Tweets*
0
Facebook likes*
0
Reddit*
0
News coverage*
0
Blogs*
0
SC clicks
2
Concepts
Immune system, Chemotherapy, Developmental biology, Endoplasmic reticulum, Gene expression, Protein, DNA, Hedgehog signaling pathway
MeSH headings
-
comments powered by Disqus

* Data courtesy of Altmetric.com