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[Autoimmune myopathy associated with statin use]

OPEN Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række | 17 Sep 2016

U Ljøstad and Å Mygland
Abstract
It is well known that statins can have a toxic effect on musculature, but less widely known that they can also trigger progressive autoimmune myopathy. Statin-associated autoimmune myopathy is characterised by proximal muscle weakness, antibodies to 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) in serum, and necrosis without lymphocytic infiltration on muscle biopsy.
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Concepts
Neuromuscular disease, Creatine kinase, Metabolism, Immune system, Muscle weakness, Statin, Muscle, Muscular system
MeSH headings
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