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DM Ferrero, J Larson, B Jacobsson, GC Di Renzo, JE Norman, JN Martin, M D'Alton, E Castelazo, CP Howson, V Sengpiel, M Bottai, JA Mayo, GM Shaw, I Verdenik, N Tul, P Velebil, S Cairns-Smith, H Rushwan, S Arulkumaran, JL Howse and JL Simpson
Abstract
Preterm birth is the most common single cause of perinatal and infant mortality, affecting 15 million infants worldwide each year with global rates increasing. Understanding of risk factors remains poor, and preventive interventions have only limited benefit. Large differences exist in preterm birth rates across high income countries. We hypothesized that understanding the basis for these wide variations could lead to interventions that reduce preterm birth incidence in countries with high rates. We thus sought to assess the contributions of known risk factors for both spontaneous and provider-initiated preterm birth in selected high income countries, estimating also the potential impact of successful interventions due to advances in research, policy and public health, or clinical practice.
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Concepts
Perinatal mortality, Medical statistics, Infant mortality, Infant, Human Development Index, Epidemiology, Preterm birth, Childbirth
MeSH headings
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